Research Project
Grant-in-Aid for Scientific Research (C)
The present study was undertaken to examine the detailed distribution and the function of brain-type fatty acid binding protein (B-FABP/FABP7), a strong binder of omega-3 fatty acids, in mouse peripheral immune organs and immune cells.B-FABP was localized to the fibroblastic reticular cells, which construct the stromal reticula in the T cell areas of the peripheral lymph nodes and spleen. In B-FABP knockout (KO) mice, the percentage of CD4^+ cells in the organs was significantly increased compared with that in wild-type mice.In the liver, B-FABP was exclusively localized in Kupffer cells. Their phagocytic activity and accumulation to injured portion were significantly decreased in KO mice.
All 2011 2010 2009 2008 Other
All Journal Article (32 results) (of which Peer Reviewed: 30 results) Presentation (45 results) Remarks (4 results)
Curr Pharm Des 17
Pages: 168-175
J Invest Dermatol 131
Pages: 604-612
J Human Genetics 56
Pages: 34-40
薬学雑誌 131
Pages: 497-502
130000678828
Curr Pharm Des
Volume: 17 Pages: 168-175
J Invest Dermatol
Volume: 131 Pages: 604-612
J Human Genetics
Volume: 56 Pages: 34-40
薬学雑誌
Volume: 131 Pages: 497-502
Histochem Cell Biol 134
Pages: 445-452
Ann Anat 192
Pages: 210-214
J Neurosci 30
Pages: 3146-3155
J Human Genetics 55
Pages: 127-130
-その数値をどう読むか- 第7版(2)
Pages: 80-82
Histochem Cell Biol
Volume: 134 Pages: 445-452
Ann Anat
Volume: 192 Pages: 210-214
J Neurosci
Volume: 30 Pages: 3146-3155
Volume: 55 Pages: 127-130
日本臨床 広範囲 血液・尿化学検査 免疫学的検査 -その数値をどう読むか- 第7版 68
Histochem Cell Biol 132
Pages: 577-584
Cell Tissue Res 338
Pages: 191-201
PLoS ONE 4
Tohoku J Exp Med 217
Pages: 185-191
薬学雑誌 129
Pages: 191-195
110007046096
時間学研究 3
Pages: 49-57
Am J Pathol 173
Pages: 1806-1817
Prost Leuko Ess Fatty Acids 79
Pages: 21-26
Immunogenetics 60
Pages: 599-607
Biochem Biophys Acta 1781
Pages: 314-320
Tohoku J Exp Med 214
Pages: 213-220
Biochem Biophys Res Commun 367
Pages: 590-596
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