| Project/Area Number |
20590602
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hygiene
|
|---|
| Research Institution | Shimane University |
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Principal Investigator |
SHIWAKU Kuninori Shimane University, 医学部, 教授 (10108384)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
嘉数 直樹 島根大学, 医学部, 准教授 (20264757)
山崎 雅之 島根大学, 医学部, 助教 (60379683)
岩本 麻実子 島根大学, 医学部, 助教 (90432616)
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| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 肥満 / メタボリックシンドローム / 耐糖能異常 / 発症要因 / 介入 / 前糖尿病 / 糖尿病 / 身体活動 |
|---|
| Research Abstract |
We conducted to predictive study for metabolic syndrome and prediabetes in cohort and interventional study. Men, especially elderly persons were popular with diabetes. Prevalence of diabetes in women increased with BMI, but there were more less than BMI18.4 than BMI18.5-22.9. Characteristics of higher decrease in HbA1c, HbA1c was higher before intervention and increased physical activity. The intervention study revealed that an increase in physical activity was important to the diabetes prevention. Non-fat mass was significantly decreased with fat mass in the intervention study using DXA. A decrease in fat in hepatocytes was related to an improvement of insulin resistance by the intervention.
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