Clarification of new mechanism of ischemic heart disease through periodontitis and identification of cause periodontitis bacterium
| Project/Area Number |
20590829
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Kumamoto University |
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Principal Investigator |
SOEJIMA Hirofumi Kumamoto University, 保健センター, 准教授 (80332881)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 歯周病スコア / 歯周病菌 / 冠動脈 / プラーク / mRNA / 冠動脈形成術 / 高感度c-reactive protein / 急性冠症候群 / バルーン / 炎症反応 / 歯周病 / 抗体価 / Toll-like receptor / 白血球 / 歯周病抗体価 / 冠動脈疾患 |
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| Research Abstract |
The relativity of the periodontitis severity and high sensitivity c-reactive protein that was the index of the inflammatory reaction of the whole body was proven. A part of coronary plaque contents adheres to the balloon after the coronary intervention. The detection of the periodontitis bacterium was tried from this balloon adhesion thing by polymerase chain reaction, then, mRNA of Prevotella intermedia and Porphyromonas gingivalis was detected.
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Report
(4 results)
Research Products
(27 results)
