Research of mechanism of synemin in neurons of midbrain
| Project/Area Number |
20591016
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurology
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| Research Institution | Gunma University |
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Principal Investigator |
MIZUNO Yuji Gunma University, 医学部, 講師 (20282395)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | synemin / desmuslin / intermediate filament / muscular dystrophy / dystrobrevin |
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| Research Abstract |
We reported that synemin transcript and its protein are more highly expressed in the midbrain and pons of C57BL/6 in 2007, using in situ hybridization and immunohistochemical analysis. In this study, we further focused on the anterior horn cells of spinal cord and showed that synemin transcript and its encoded protein also co-localize in the anterior horn cells.
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Report
(4 results)
Research Products
(20 results)
