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Genome and Gene expression profiling of EBV-positive diffuse large cell lymphoma of the elderly

Research Project

Project/Area Number 20591142
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Hematology
Research InstitutionAichi Cancer Center Research Institute

Principal Investigator

YAMAMOTO Kazuhito  Aichi Cancer Center Research Institute, 遺伝子医療研究部, 研究員 (60250247)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords血液腫瘍学 / 悪性リンパ腫 / Epstein-Barr virus / 加齢 / ゲノム異常 / アレイCGH法 / 免疫異常 / 網羅的発現解析
Research Abstract

We explored gene-expression profiling to compare EBV-positive diffuse large B-cell lymphoma (DLBCL) (synonyms: age-related EBV+LPD) with EBV-negative DLBCL. In age-related EBV+LPD, NOD-like receptor and JAK-STAT signaling pathway was showed to be augmented, suggesting that age-related EBV+LPD was characterized by alternation of immune and inflammatory responses.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (54 results)

All 2011 2010 2009 2008

All Journal Article (37 results) (of which Peer Reviewed: 9 results) Presentation (12 results) Book (5 results)

  • [Journal Article] Nodal relapse after Helicobacter pylori eradication in a patient with primary localized gastric mucosa-associated lymphoid tissue lymphoma.2011

    • Author(s)
      Kato H, Kagami Y, Kodaira T, Oka S, Oki Y, Chihara D, Taji H, Yatabe Y, Nakamura T, Nakamura S, Seto M, Yamamoto K, Morishima Y.
    • Journal Title

      Am J Gastroenterol. 106(3)

      Pages: 549-551

    • Related Report
      2010 Final Research Report
  • [Journal Article] High maximum standard uptake value (SUVmax) on PET scan is associated with shorter survival in patients with diffuse large B cell lymphoma.2011

    • Author(s)
      Chihara D, Oki Y, Onoda H, Taji H, Yamamoto K, Tamaki T, Morishima Y.
    • Journal Title

      Int J Hematol. 93(4)

      Pages: 502-508

    • NAID

      10029534614

    • Related Report
      2010 Final Research Report
  • [Journal Article] T細胞性リンパ系腫瘍に対する新規薬剤の導入による新たな治療展開2011

    • Author(s)
      牛島洋子、山本一仁
    • Journal Title

      注目される造血器腫瘍に対する新規薬剤の現状と展望 血液内科 62(1)

      Pages: 51-57

    • Related Report
      2010 Final Research Report
  • [Journal Article] R-CHOP therapy for MALT lymphoma of the rectum.2010

    • Author(s)
      Chihara D., Kagami Y., Oki Y., Kato H., Onoda H., Ine S., Taji H., Yamamoto K., Morishima Y.
    • Journal Title

      Eur J Haematol. 84(1)

      Pages: 84-86

    • Related Report
      2010 Final Research Report
  • [Journal Article] BCR-ABL-independent and RAS / MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4.2010

    • Author(s)
      Suzuki M., Abe A., Imagama S., Nomura Y., Tanizaki R., Minami Y., Hayakawa F., Ito Y., Katsumi A., Yamamoto K., Emi N., Kiyoi H., Naoe T.
    • Journal Title

      Eur J Haematol 84(3)

      Pages: 229-238

    • Related Report
      2010 Final Research Report
  • [Journal Article] Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients with Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma.2010

    • Author(s)
      Yamamoto K., Utsunomiya A., Tobinai K., Tsukasaki K., Uike N., Uozumi K., Yamaguchi K., Yamada Y., Hanada S., Tamura K., Nakamura S., Inagaki H., Ohshima K., Kiyoi H., Ishida T., Matsushima K., Akinaga S., Ogura M., Tomonaga M., Ueda R.
    • Journal Title

      J.Clin.Oncol. 28(9)

      Pages: 1591-1598

    • Related Report
      2010 Final Research Report
  • [Journal Article] Primary gastric diffuse large B-cell Lymphoma (DLBCL) : analyses of prognostic factors and value of pretreatment FDG-PET scan.2010

    • Author(s)
      Chihara D., Oki Y., Ine S., Kato H., Onoda H., Taji H., Kagami Y., Yamamoto K., Morishima Y.
    • Journal Title

      Eur J Haematol. 84(6)

      Pages: 493-498

    • Related Report
      2010 Final Research Report
  • [Journal Article] Central nervous system involvement in intravascular large B-cell lymphoma : A retrospective analysis of 109 patients.2010

    • Author(s)
      Shimada K., Murase T., Matsue K., Okamoto M., Ichikawa N., Tsukamoto N., Niitsu N., Miwa H., Asaoku H., Kosugi H., Kikuchi A., Matsumoto M., Saburi Y., Masaki Y., Yamamoto K., Yamaguchi M., Nakamura S., Naoe T., Kinoshita T. for the IVL Study Group in Japan
    • Journal Title

      Cancer Sci. 101(6)

      Pages: 1480-1486

    • NAID

      10026593809

    • Related Report
      2010 Final Research Report
  • [Journal Article] Clinical impact and predisposing factors of delayed-onset neutropenia after autologous hematopoietic stem-cell transplantation for B-cell non-Hodgkin lymphoma: association with an incremental risk of infectious events.2010

    • Author(s)
      Kato H., Yamamoto K., Matsuo K., Oki Y., Taji H., Kuwatsuka Y., Seto M., Kagami Y., Morishima Y.
    • Journal Title

      Ann Oncol. 21(8)

      Pages: 1699-1705

    • Related Report
      2010 Final Research Report
  • [Journal Article] Trough plasma concentration of imatinib reflects BCR-ABL kinase inhibitory activity and clinical response in chronic-phase chronic myeloid leukemia : a report from the BINGO study.2010

    • Author(s)
      Ishikawa Y, Kiyoi H, Watanabe K, Miyamura K, Nakano Y, Kitamura K, Kohno A, Sugiura I, Yokozawa T, Hanamura A, Yamamoto K, Iida H, Emi N, Suzuki R, Ohnishi K, Naoe T.
    • Journal Title

      Cancer Sci. 101(10)

      Pages: 2186-2192

    • NAID

      10027832450

    • Related Report
      2010 Final Research Report
  • [Journal Article] CCR4陽性末梢T細胞リンパ腫に対する抗CCR4抗体の臨床試験2010

    • Author(s)
      山本一仁
    • Journal Title

      特集:T/NK細胞腫瘍研究の新展開 血液・腫瘍科 60(5)

      Pages: 614-621

    • Related Report
      2010 Final Research Report
  • [Journal Article] 分子標的治療薬に関連する毒性とその対策2010

    • Author(s)
      大熊ひでみ、山本一仁
    • Journal Title

      特集:白血病診療essentials.日常診療に必要な最新の診断と治療 内科 106(2)

      Pages: 285-290

    • Related Report
      2010 Final Research Report
  • [Journal Article] Alemtuzumab.連載講座2010

    • Author(s)
      山本一仁
    • Journal Title

      分子標的治療薬 Biotherapy 24(5)

      Pages: 416-420

    • Related Report
      2010 Final Research Report
  • [Journal Article] Primary gastric diffuse large B-cell Lymphoma (DLBCL) : analyses of prognostic factors and value of pretreatment FDG-PET scan2010

    • Author(s)
      Chihara D.
    • Journal Title

      European J Haematology

      Volume: 84 Pages: 493-498

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Central nervous system involvement in intravascular large B-cell lymphoma : A retrospective analysis of 109 patients2010

    • Author(s)
      Shimada K.
    • Journal Title

      Cancer Science

      Volume: 101 Pages: 1480-1486

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical impact and predisposing factors of delayed-onset neutropenia after autologous hematopoietic stem-cell transplantation for B-cell non-Hodgkin lymphoma : association with an incremental risk of infectious events2010

    • Author(s)
      Kato H.
    • Journal Title

      Annals of Oncology

      Volume: 21 Pages: 1699-1705

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] BCR-ABL-independent and RAS/MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB42010

    • Author(s)
      Suzuki, M.
    • Journal Title

      European Journal of Haematology 84

      Pages: 229-238

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients with Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma2010

    • Author(s)
      Yamamoto, K.
    • Journal Title

      Journal of Clinical Oncolcogy 28

      Pages: 1591-1598

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Primary cutaneous T-cell lymphoma of unspecified type with cytotoxic phenotype : clinicopathological analysis of 27 patients.2009

    • Author(s)
      Hagiwara M., Takata K., Shimoyama Y., Yamamoto K., Takahashi E., Asano N., Iwase Y., Okazaki Y., Tamada Y., Yoshino T., Tomita Y., Nakamura S.
    • Journal Title

      Cancer Sci. 100(1)

      Pages: 33-41

    • NAID

      10025141167

    • Related Report
      2010 Final Research Report
  • [Journal Article] Age-related EBV-associated B-cell lymphoproliferative disorders : comparison with EBV-positive classical Hodgkin lymphoma in elderly patients.2009

    • Author(s)
      Asano N., Yamamoto K., Tamaru J., Oyama T., Ishida F., Ohshima K., Yoshino T., Nakamura N., Mori S., Yoshie O., Shimoyama Y., Morishima Y., Kinoshita T., Nakamura S.
    • Journal Title

      Blood 113(12)

      Pages: 2629-2636

    • Related Report
      2010 Final Research Report
  • [Journal Article] Analysis of prognostic factors in peripheral T-cell lymphoma : prognostic value of serum albumin and mediastinal lymphadenopathy.2009

    • Author(s)
      Chihara D., Oki Y., Ine S., Yamamoto K., Kato H., Taji H., Kagami Y., Yatabe Y., Nakamura S., Morishima Y.
    • Journal Title

      Leuk Lymphoma 50(12)

      Pages: 1999-2004

    • Related Report
      2010 Final Research Report
  • [Journal Article] Favorable consolidative effect of high-dose melphalan and total-body irradiation followed by autologous peripheral blood stem cell transplantation after rituximab-containing induction chemotherapy with in vivo purging in relapsed or refractory follicular lymphoma.2009

    • Author(s)
      Kato H., Taji H., Ogura M., Kagami Y., Oki Y., Tsujimura A., Fuwa N., Kodaira T., Seto M., Yamamoto K., Morishima Y.
    • Journal Title

      Clin Lymphoma Myeloma 9(6)

      Pages: 443-448

    • Related Report
      2010 Final Research Report
  • [Journal Article] Age-related EBV-associated B-cell lymphoproliferative disorders : diagnostic approach to a newly recognized clinicopathological entity.2009

    • Author(s)
      Shimoyama Y., Asano N., Kojima M., Morishima S., Yamamoto K, Oyama T., Kinoshita T., Nakamura S.
    • Journal Title

      Pathol Int. 59(12)

      Pages: 835-843

    • NAID

      10027382347

    • Related Report
      2010 Final Research Report
  • [Journal Article] T細胞リンパ腫-成熟(末梢性)T細胞リンパ腫を中心に2009

    • Author(s)
      山本一仁
    • Journal Title

      特集:がんの分子標的治療の現状 Medico 40(6)

    • Related Report
      2010 Final Research Report
  • [Journal Article] Age-related EBV-associated B-cell lymphoproliferative disorders : comparison with EBV-positive classical Hodgkin lymphoma in elderly patients2009

    • Author(s)
      Asano, N.
    • Journal Title

      Blood 113

      Pages: 2629-2636

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-related EBV-associated B-cell lymphoproliferative disorders : comparison with EBV-positive classical Hodgkin lymphoma in elderly patients2009

    • Author(s)
      Asano N.
    • Journal Title

      Blood 113

      Pages: 2629-2636

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase II study of a salvage regimen using cyclophosphamide, high-dose cytarabine, dexamethasone, etoposide and rituximab (CHASER) in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.2008

    • Author(s)
      Oki Y., Ogura M., Kato H., Kikuch A., Taji H., Kagami Y., Oshiro A., Tsujimura A., Yamamoto K., Morishima Y.
    • Journal Title

      Cancer Science 99(1)

      Pages: 178-184

    • Related Report
      2010 Final Research Report
  • [Journal Article] Nagoya Blood and Marrow Transplantation Group : Hematopoietic stem cell transplantation for acute promyelocytic leukemia in second or third complete remission : a retrospective analysis in the Nagoya Blood and Marrow Transplantation Group.2008

    • Author(s)
      Kohno A., Morishita Y., Iida H., Yanada M., Uchida T., Hamaguchi M., Sawa M., Sugiura I., Yamamoto K., Mizuta S, Sao H., Naoe T., Miyamura K.
    • Journal Title

      Int J Hematol. 87(2)

      Pages: 210-216

    • Related Report
      2010 Final Research Report
  • [Journal Article] Prognostic value of serum soluble interleukin-2 receptor level in patients with diffuse large B cell lymphoma, treated with CHOP-or RCHOP-based therapy.2008

    • Author(s)
      Oki Y, Kato H, Matsuo K, Kuwatsuka Y, Taji H, Yamamoto K, Kagami Y, Morishima Y.
    • Journal Title

      Leuk Lymphoma 49(7)

      Pages: 1345-1351

    • Related Report
      2010 Final Research Report
  • [Journal Article] A retrospective analysis of intravascular large B-cell lymphoma (IVLBCL) treated with rituximab-containing chemotherapies.2008

    • Author(s)
      Shimada K., Matsue K., Yamamoto K., Murase T., Ichikawa N., Okamoto M., Niitsu N., Kosugi H., Tsukamoto N., Miwa H., Asaoku H., Kikuchi A., Matsumoto M., Saburi Y., Masaki Y., Yamaguchi M., Nakamura S., Naoe T., Kinoshita T.
    • Journal Title

      J.Clin.Oncol. 26(19)

      Pages: 3189-3195

    • Related Report
      2010 Final Research Report
  • [Journal Article] Low absolute lymphocyte count is a poor prognostic marker in patients with diffuse large B-cell lymphoma and suggests patients' survival benefit from rituximab.2008

    • Author(s)
      Oki Y., Yamamoto K., Kato H., Kuwatsuka Y., Taji H., Kagami Y., Morishima Y.
    • Journal Title

      Eur J Haematol. 81(6)

      Pages: 448-453

    • Related Report
      2010 Final Research Report
  • [Journal Article] Age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorders : A review with a special reference to lymphomas surrounding this newly recognized clinicopathologic disease.2008

    • Author(s)
      Shimoyama Y, Yamamoto K, Asano N, Oyama T, Kinoshita T, Nakamura S
    • Journal Title

      Cancer Sci. 99(6)

      Pages: 1085-1091

    • Related Report
      2010 Final Research Report
  • [Journal Article] 加齢関連EBV陽性B細胞性リンパ増殖性疾患2008

    • Author(s)
      山本一仁、中村栄男
    • Journal Title

      特集:EBウイルス(EBV)とリンパ網内系疾患 血液・腫瘍科 56(3)

      Pages: 294-298

    • Related Report
      2010 Final Research Report
  • [Journal Article] 《悪性リンパ腫を極める:各病理組織型に基づく治療法》マントル細胞リンパ腫2008

    • Author(s)
      山本一仁、鍬塚八千代
    • Journal Title

      特集:悪性リンパ腫診療update in 2008-最新のエビデンスに基づく診断と治療 内科 102(2)

      Pages: 300-305

    • Related Report
      2010 Final Research Report
  • [Journal Article] 消化管follicular lymphomaの治療指針2008

    • Author(s)
      中村常哉、田近正洋、河合宏紀、鏡味良豊、山本一仁、加藤春美、横井太紀雄、谷田部恭、中村栄男
    • Journal Title

      胃と腸 43(7)

      Pages: 1081-1084

    • Related Report
      2010 Final Research Report
  • [Journal Article] Age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorders : A review with a special reference to lymphomas surrounding this newly recognized clinicopathologic disease2008

    • Author(s)
      Shimoyama Y.
    • Journal Title

      Cancer Science 99

      Pages: 1085-1091

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A retrospective analysis of intravascular large B-cell lymphoma (IVLBCL) treated with rituximab-containing chemotherapies2008

    • Author(s)
      Shimada K.
    • Journal Title

      Journal of Clinical Oncology 26

      Pages: 3189-3195

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Clinical trials of a defucosylated anti-CCR4 antibody for ATL and PTCL(Joint Symposium with Japanese Society of Lymphoreticular Tissue Research、英語発表).2010

    • Author(s)
      山本一仁
    • Organizer
      第72回日本血液学会総会
    • Place of Presentation
      横浜市
    • Year and Date
      2010-09-26
    • Related Report
      2010 Final Research Report
  • [Presentation] Clinical trials of a defucosylated anti-CCR4 antibody for ATL and PTCL2010

    • Author(s)
      Kazuhito Yamamoto
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      神奈川県横浜市パシフィコ横浜
    • Year and Date
      2010-09-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Multicenter Phase II Study of KW-0761, a Defucosylated Anti-CCR4 Antibody, In Relapsed Patients with Adult T-Cell Leukemia-Lymphoma (ATL) (Oral Session).2010

    • Author(s)
      Takashi Ishida, Tatsuro Joh, Naokuni Uike, Kazuhito Yamamoto, Atae Utsunomiya , Shinichiro Yoshida, Yoshio Saburi, Toshihiro Miyamoto, Shigeki Takemoto, Hitoshi Suzushima, Kunihiro Tsukasaki, Kisato Nosaka, Hiroshi Fujiwara, Kenji Ishitsuka, Hiroshi Inagaki, Michinori Ogura, Shiro Akinaga, Masao Tomonaga, Kensei Tobinai, Ryuzo Ueda
    • Organizer
      The 52nd Annual Meeting of American Society of Hematology
    • Place of Presentation
      Orlando, FL, U.S.A.
    • Related Report
      2010 Final Research Report
  • [Presentation] Increased Peripheral T Cell Responses to EBV-Infected Cells with Frequent Detection of EBV-DNA In Plasma and Viral mRNA In Peripheral B-Cells In Immunocompetent EBV-Positive Diffuse Large B-Cell Lymphoma Patients (Poster Session).2010

    • Author(s)
      Satoko Morishima, Kazuhito Yamamoto, Hiroshi Kimura, Seiko Iwata, Tomohiro Kinoshita, Hirokazu Nagai, Isamu Sugiura, Keitaro Tsushita, Yoshitoyo Kagami, Koichi Miyamura, Kiyotaka Kuzushima, Shigeo Nakamura, Yasuo Morishima.
    • Organizer
      The 52nd Annual Meeting of American Society of Hematology
    • Place of Presentation
      Orlando, FL, U.S.A.
    • Related Report
      2010 Final Research Report
  • [Presentation] Safety and Risk of Allogeneic Peripheral Blood Stem Cell Donation : The Comprehensive Report of Nation-Wide Consecutively Pre-Registered 3,264 Family Donor Survey In 10years Project by Japan Society for Hematopoietic Cell Transplantation (Poster Session).2010

    • Author(s)
      Yoshihisa Kodera, Kazuhito Yamamoto, Shunichi Kato, Mine Harada, Yoshinobu Kanda, Nobuyuki Hamajima, Shigetaka Asano, Yasuo Ikeda, Masahiro Imamura, Keisei Kawa, Yasuo Morishima, Tatsutoshi Nakahat, Mitsune Tanimoto, Ryuji Tanosaki, Shintaro Shiobara, Sung-Won Kim, Koji Nagafuji, Masayuki Hino, Koichi Miyamura, Ritsuro Suzuki.
    • Organizer
      The 52nd Annual Meeting of American Society of Hematology
    • Place of Presentation
      Orlando, FL, U.S.A.
    • Related Report
      2010 Final Research Report
  • [Presentation] A Retrospective Analysis on Prognostic Factors of Angioimmunoblastic T-Cell Lymphoma : a Multicenter Cooperative Study In Japan (Poster).2010

    • Author(s)
      Takashi Tokunaga, Kazuyuki Shimada, Kazuhito Yamamoto, Dai Chihara, Takuji Ichihashi, Rika Oshima, Mitsune Tanimoto, Toshihiro Iwasaki, Atsushi Isoda, Akira Sakai, Hikaru Kobayashi, Kunio Kitamura, Kosei Matsue, Masafumi Taniwaki, Sadahiro Tamashima, Yoshio Saburi, Taro Masunari, Tomoki Naoe, Shigeo Nakamura, Tomohiro Kinoshita.
    • Organizer
      The 52nd Annual Meeting of American Society of Hematology
    • Place of Presentation
      Orlando, FL, U.S.A.
    • Related Report
      2010 Final Research Report
  • [Presentation] Incidence and Risk Factors for Central Nervous System (CNS) Relapse In Patients with Diffuse Large B-Cell Lymphoma (DLBCL) : Analysis with Competing Risk Regression (CRR) Model (Poster Session).2010

    • Author(s)
      Dai Chihara, Yasuhiro Oki, Keitaro Matsuo, Hiroshi Onoda, Hirofumi Taji, Kazuhito Yamamoto, Yasuo Morishima
    • Organizer
      The 52nd Annual Meeting of American Society of Hematology.
    • Place of Presentation
      Orlando, FL, U.S.A.
    • Related Report
      2010 Final Research Report
  • [Presentation] ダサチニブの慢性期慢性骨髄性白血病に対する1 日用量100mg 投与の臨床第II相試験の長期投与成績(口頭)2009

    • Author(s)
      山本一仁、岡田昌也、坂巻壽、小林幸夫、安藤潔、中川靖章、大西一功、谷脇雅史、宇都宮與、上田享司、大野竜三
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      京都市
    • Year and Date
      2009-10-24
    • Related Report
      2010 Final Research Report
  • [Presentation] Gastric Diffuse Large B-Cell Lymphoma : Analyses of Prognostic Factors and Value of Pretreatment FDG-PET Scan (Poster Session).2009

    • Author(s)
      Dai Chihara, Yasuhiro Oki, Shouji Ine, Hiroshi Onoda, Harumi Kato, Hirofumi Taji, Yoshitoyo Kagami, Kazuhito Yamamoto, Yasuo Morishima
    • Organizer
      51st Annual Meeting of the American Society of Hematology
    • Place of Presentation
      New Orleans, LA, U.S.A.,
    • Related Report
      2010 Final Research Report
  • [Presentation] 血管内大細胞型B細胞リンパ腫に対するrituximab 併用化学療法の有用性の検討(プレナリーセッション).2008

    • Author(s)
      島田和之、末長孝夫、山本一仁、村瀬卓平、市川直明、岡本昌隆、新津望。小杉浩史、塚本憲史、三輪啓志、麻奥英綱、菊池我子、松本守夫、田村和夫、佐分利能生、正木康史、柏村眞、吉田喬、山口素子、中村栄男、直江知樹、木下朝博
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都市
    • Year and Date
      2008-10-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 愛知県がんセンター中央病院におけるimatinib抵抗性・不耐容慢性骨髄性白血病に対するdasatinibの治験成績(ポスター).2008

    • Author(s)
      山本一仁、大木康弘、田地浩史、加藤春美、鏡味良豊、森島泰雄
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都市
    • Year and Date
      2008-10-10
    • Related Report
      2010 Final Research Report
  • [Presentation] Phase I Study of KW-0761, a Defucosylated Anti-CCR4 Antibody, in Relapsed Patients (Pts) with Adult T-Cell Leukemia-Lymphoma (ATL) or Peripheral T-Cell Lymphoma (PTCL) : Updated Results (Poster Session).2008

    • Author(s)
      Yamamoto K., Tobinai K., Utsunomiya A., Tsukasaki K., Uike N., Uozumi K., Tomonaga M., Matsushima K., Shitara K., Akinaga S., Ueda R.
    • Organizer
      50th Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Francisco, CA, U.S.A.
    • Related Report
      2010 Final Research Report
  • [Book] 血液疾患エキスパート「悪性リンパ腫」(加齢性EBウイルス陽性B細胞リンパ腫.)2010

    • Author(s)
      山本一仁
    • Publisher
      中外医学社
    • Related Report
      2010 Final Research Report
  • [Book] 血液診療エキスパート悪性リンパ腫「加齢性EBウイルス陽性B細胞リンパ腫」2010

    • Author(s)
      山本一仁
    • Publisher
      中外医学社
    • Related Report
      2010 Annual Research Report
  • [Book] 慢性リンパ性白血病の適切な初期治療とそのタイミングは?臨床に直結する血液疾患診療のエビデンス2009

    • Author(s)
      山本一仁、大木康弘
    • Publisher
      文光堂
    • Related Report
      2010 Final Research Report
  • [Book] がん化学療法・分子標的治療update(その他のモノクローナル抗体)2009

    • Author(s)
      山本一仁、森島泰雄
    • Publisher
      中外医学社
    • Related Report
      2010 Final Research Report
  • [Book] 悪性リンパ腫治療マニュアル(改訂第3版)(悪性リンパ腫に対する自家末梢血幹細胞移植併用大量化学療法の原理と実際.)2009

    • Author(s)
      山本一仁
    • Publisher
      南江堂
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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