Role of ROD1 in the pathogenesis of allergic inflammation
Project/Area Number |
20591186
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
膠原病・アレルギー・感染症内科学
|
Research Institution | Nagoya University |
Principal Investigator |
MASUDA Aklo Nagoya University, 医学系研究科, 助教 (10343203)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | ROD1 / RNA / RNA結合タンパク / splicing / RODI |
Research Abstract |
We found that ROD1 binds to GU/GC rich regions in introns to regulate splicing. We succeeded to analyze RNA-protein interaction with CLIP method, which is a quite effective method established recently. We identified 4 isoforms of ROD1 and found difference in the ability of nuclear-cytoplasmic shuttling.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article]2009
Author(s)
Ohno K, Ito M, Masuda A.
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Journal Title
Nihon Shinkei Seishin Yakurigaku Zasshi. 29(4)
Pages: 145-151
Related Report
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[Journal Article]2009
Author(s)
Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K.
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Journal Title
Neuroscience Letters 453
Pages: 81-85
Related Report
Peer Reviewed
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[Journal Article]2009
Author(s)
Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K.
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Journal Title
Hum Mol Genet 18
Pages: 1229-1237
Related Report
Peer Reviewed
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[Journal Article]2009
Author(s)
Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, Ohnishi T.
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Journal Title
J Bone Miner Res. 24(3)
Pages: 398-410
Related Report
Peer Reviewed
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[Journal Article]2008
Author(s)
Masuda A, Shen X-M, Ito M, Matsuura T, Engel AG, Ohno K.
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Journal Title
Hum Mol Genet. 17
Pages: 4022-4035
Related Report
Peer Reviewed
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[Journal Article]2008
Author(s)
Ito M, Masuda A, Jinno S, Katagiri T, Krejci E, Ohno K.
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Journal Title
Chem Biol Interact. 175
Pages: 346-348
Related Report
Peer Reviewed
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