Project/Area Number |
20591431
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Radiation science
|
Research Institution | Hokkaido University |
Principal Investigator |
KATOH Chietsugu Hokkaido University, 大学院・保健科学研究院, 准教授 (10292012)
|
Co-Investigator(Kenkyū-buntansha) |
YOSHINAGA Keiichirou 北海道大学, 大学院・医学研究科, 准教授 (30435961)
志賀 哲 北海道大学, 大学院・医学研究科, 講師 (80374495)
|
Co-Investigator(Renkei-kenkyūsha) |
SHIGA Tohru 北海道大学, 大学院・医学研究科, 講師 (80374495)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2008: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
|
Keywords | 虚血性心疾患 / PET / ルビジウム82 / 心筋血流 / 定量測定 / ルビジウム / コンパートメントモデル解析 / 再現性 |
Research Abstract |
Three-dimensional (3D) PET with 82Rb yields myocardial image data with much spillover fraction from the blood. To calculate the regional myocardial blood flow (MBF) with 82Rb myocardial 3D PET, we developed a new algorithm to suppress the spillover using a non-uniform least squared fitting with a weighted function using a blood time-activity curve.
|