The protective effect of percutaneous isolated hepatic perfusion on high-risk group for the recurrence of Hepatocellular carcinoma after resection
Project/Area Number |
20591611
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Digestive surgery
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Research Institution | Kobe University |
Principal Investigator |
KU Yonson Kobe University, 大学院・医学研究科, 教授 (40195615)
|
Co-Investigator(Kenkyū-buntansha) |
FUKUMOTO Takumi 神戸大学, 大学院・医学研究科, 准教授 (70379402)
KUSUNOKI Nobuya 神戸大学, 医学部付属病院, 准教授 (10379406)
KIDO Masahiro 神戸大学, 医学部付属病院, 講師 (00403246)
尾形 哲 神戸大学, 医学部附属病院, 医員 (40444583)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 肝細胞癌 / 再発肝癌 / 経皮的肝灌流化学療法 / 肝内再発 / 肝切除 / 経皮的肝灌流 |
Research Abstract |
Hepatic resection remains the only therapeutic option for improved survival in the patients with hepatocellular carcinoma (HCC). However, a high incidence of recurrence after resection is life-threatening problem. In this study, we proposed percutaneous isolated hepatic perfusion (PIHP), a novel and potent regional chemotherapeutic regimen can achieve the protection against high-risk group for the recurrence of HCC after resection. PIHP after hepatic resection improved overall survival. In conclusion, dual treatment of resection and PIHP can offer an innovative strategy for resectable HCC treatment.
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Report
(4 results)
Research Products
(97 results)
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[Journal Article] Predictors of malignant intraductal papillary mucinous neoplasm of the pancreas.2010
Author(s)
Mimura T, Masuda A, Matsumoto I, Shiomi H, Yoshida S, Sugimoto M, Sanuki T, Yoshida M, Fujita T, Kutsumi H, Ku Y, Azuma T.
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Journal Title
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Peer Reviewed
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[Journal Article] Resection of gallbladder cancer with hepatic metastasis after chemotherapy with gemcitabine.2008
Author(s)
Morimoto H, Ajiki T, Takase S, Fujita T, Matsumoto T, Mita Y, Matsumoto I, Fujino Y, Suzuki Y, Kuroda Y, Ku Y.
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Journal Title
J Hepatobiliary Pancreat Surg. 15
Pages: 655-658
Related Report
Peer Reviewed
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[Journal Article] The effectiveness of particle radiotherapy for hepatocellular carcinoma accompanied with inferior vena cava tumor thrombus.
Author(s)
Komatsu S, Fukumoto T, Demizu Y, Miyawaki D, Terashima K, Sasaki R, Yamada I, Hori Y, Hishikawa Y, Ku Y, Murakami M.
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Journal Title
J Gastroenterol in press.
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Peer Reviewed
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[Book] 外科2011
Author(s)
松本逸平、白川幸代、福本巧、具英成
Publisher
南光堂
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[Book] 膵臓2011
Author(s)
松本逸平、新関亮、福本巧、具英成
Publisher
膵臓学会
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[Book] 手術2010
Author(s)
土田忍、冨永正寛、岩崎武、具英成
Publisher
金原出版
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[Book] 外科2009
Author(s)
村上昌雄、小松昇平、福本巧、具英成、菱川良夫
Publisher
南光堂
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