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Epidermal cooling for spinal cord protection against ischemia

Research Project

Project/Area Number 20591641
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionTohoku University

Principal Investigator

TABAYASHI Koichi  Tohoku University, 大学院・医学系・研究科, 名誉教授 (90142942)

Co-Investigator(Kenkyū-buntansha) SAIKI Yoshikatsu  東北大学, 大学院・医学系研究科, 教授 (50372298)
KAWAMOTO Shunsuke  東北大学, 大学院・医学系研究科, 准教授 (20400244)
MOTOYOSHI Naotaka  東北大学, 病院, 講師 (40375093)
MARUYAMA Shigenao  東北大学, 流体科学研究所, 教授 (80173962)
KOMIYA Atsuki  東北大学, 流体科学研究所, 助教 (60371142)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords心臓大血管外科学 / 神経保護 / 脊髄保護 / 局所冷却
Research Abstract

Epidermal cooling may bring protective effect against ischemia on deep tissue such as spinal cord which can be suffered from ischemia during clinical thoracoabdominal aortic repair. Computed simulation model on deep tissue temperature change by epidermal cooling has been established by the experimental evaluations both on animal and human models. However, clinical application was not accepted because the preliminary study showed that mild frostbite occurred on normal tissue after epidermal cooling.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (5 results)

All 2009 2008 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Remarks (1 results)

  • [Journal Article] Development and estimation of a novel cryoprobe utilizing the Peltier effect for precise and safe cryosurgery.2009

    • Author(s)
      Takeda H, Maruyama S, Okajima J, Aiba S, Komiya A.
    • Journal Title

      Cryobiology. 59(3)

      Pages: 275-84

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effect of using some common white pigments on thermal and aesthetic performances of pigmented coatings.2009

    • Author(s)
      Baneshi M, Maruyama S, Nakai H, Komiya A.
    • Journal Title

      J thermal Sci Tech 1

      Pages: 131-45

    • NAID

      130000134257

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation methods for radiative heat transfer in polydisperse water droplets.2008

    • Author(s)
      Maruyama S, Nakai H, Komiya A.
    • Journal Title

      J Quant Spect Radia Transfer. 109(1)

      Pages: 1-15

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of perfusion cooling of the epidural space and cerebral fluid drainage during repair of extent I and II thoracoabdominal aneuyrysm2008

    • Author(s)
      Tabayashi K
    • Journal Title

      J Cardiovasc Surg (Torino) Dec ; 49(6)

      Pages: 749-755

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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