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Technological development of the atmospheric low-temperature plasma to treat the tendon healing and adhesion

Research Project

Project/Area Number 20591755
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionShimane University

Principal Investigator

UCHIO Yuji  Shimane University, 医学部, 教授 (20223547)

Co-Investigator(Kenkyū-buntansha) MORI Ryuji  島根大学, プロジェクト研究推進機構, 准教授 (40263537)
NAKAI Takahisa  島根大学, 総合理工学部, 准教授 (90314616)
Research Collaborator IMADE Shinji  島根大学, 医学部, 助教 (10581077)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords腱 / 外傷 / 癒着 / 大気圧プラズマ / 予防 / 繊維芽細胞 / 酸素 / 窒素 / 線維芽細胞
Research Abstract

The effect of atmospheric low-temperature plasma on post-operative adhesion was observed. The chemical composition on the surface of the treated collagen tissue was changed. The biological activities of fibroblasts, which were cultured on the treated tissue, were inhibited. The in vivo adhesion of the tendon was tended to inhibited, although it was influenced by the post-operative activities.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (9 results)

All 2010 2009 2008 Other

All Journal Article (2 results) (of which Peer Reviewed: 1 results) Presentation (4 results) Remarks (3 results)

  • [Journal Article] Effect of implant surface roughness on bone fixation : the differences between bone and metal pegs.2009

    • Author(s)
      Imade S, Mori R, Uchio Y, Furuya S.
    • Journal Title

      Journal of Orthopaedic Science. 14

      Pages: 652-657

    • NAID

      10025588527

    • Related Report
      2010 Final Research Report
  • [Journal Article] Effect of implant surface roughness on bone fixation : the differences between bone and metal pegs.2009

    • Author(s)
      Imade S, Mori R, Uchio Y, Furuya S
    • Journal Title

      Journal of Orthopaedic Science 14

      Pages: 652-627

    • NAID

      10025588527

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] ナノデバイスとプラズマ技術を用いた治療法の開発2010

    • Author(s)
      今出真司、森隆治、内尾祐司
    • Organizer
      プラズマ生物学シンポジウム
    • Place of Presentation
      大阪大学
    • Year and Date
      2010-02-05
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] The 3rd Workshop on Biological Applications of Plasma/Photon Processing.2009

    • Author(s)
      森隆治
    • Organizer
      医療における大気圧プラズマの可能性
    • Place of Presentation
      大阪
    • Year and Date
      2009-01-29
    • Related Report
      2010 Final Research Report
  • [Presentation] 骨癒合に対するプラズマ表面処理の影響2009

    • Author(s)
      今出真司, 森隆治, 内尾祐司
    • Organizer
      第24回日本整形外科学会基礎学術集会
    • Place of Presentation
      横浜
    • Related Report
      2010 Final Research Report
  • [Presentation] 生体内の癒着を防止する大気圧プラズマ治療2008

    • Author(s)
      森隆治, 今出真司, 浦山卓也, 高木康治
    • Organizer
      第25回プラズマ・核融合学会年会
    • Place of Presentation
      宇都宮
    • Related Report
      2010 Final Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.med.shimane-u.ac.jp/orthop/study/index.html

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://www.med.shimane-u.ac.jp/orthop/study/index.html

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.shimane-u.ac.jp/orthop/study/index.html

    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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