| Project/Area Number |
20591811
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
MIZOBE Toshiki Kyoto Prefectural University of Medicine, 医学研究科, 講師 (50239266)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Hideo 京都府立医科大学, 医学研究科, 准教授 (60236619)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | アドレナリン受容体 / FP / 遺伝子改変マウス / デクスメデトミジン / CALI / GFP / CALl |
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| Research Abstract |
This project is to make transgenic mouse with alpha2A adrenergic receptor (alpha2A AR) fused with green fluorescent protein (GFP), derived from jellyfish, Aequorea Victoria. We are successfully able to make transgenic mouse with alpha2A AR fused with GFP. Thisfusion protein has the same function and expression as the wild type has. This transgenicmouse will be a great molecular tool to analyze the development, distribution, and function of alpha2A adrenoceptor subtype.
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