| Project/Area Number |
20591956
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
ASATO Tsuyoshi University of the Ryukyus, 大学院・医学研究科, 助教 (40253950)
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| Co-Investigator(Renkei-kenkyūsha) |
NAGAI Yutaka 琉球大学, 医学部附属病院, 講師 (70305209)
INAMINE Morihiko 琉球大学, 医学研究科, 助教 (90437989)
KARIYA Ken-Ichi 琉球大学, 医学研究科, 教授 (40263371)
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| Research Collaborator |
YAMASHIRO Yoshito 琉球大学, 医学研究科・博士課程, 日本学術振興会特別研究員
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| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 子宮頸癌 / 放射線治療 / 子宮頚癌 |
|---|
| Research Abstract |
The present study was conducted in order to obtain data that serve as a basis for developing novel molecular markers for prediction of the outcome of radiotherapy in patients with cervical cancer. Subjects were selected from cases that were sensitive or resistant to the concurrent chemoradiotherapy (CCRT). Comprehensive protein expression profiles of pre-threapy biopsy specimen were compared between the sensitive and resistant cases. Eight proteins were identified that were expressed only in sensitive cases, while 18 proteins were identified that were expressed only in resistant cases.
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