Investigation and functional analysis of microRNAs in lens and identification of cataract-related genes
| Project/Area Number |
20592036
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | University of Fukui |
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Principal Investigator |
KUBO Eri University of Fukui, 医学部, 准教授 (10262619)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | micro RNA / 水晶体の発達 / 白内障 / Tropomyosin / Peroxiredoxin6 / microRNA |
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| Research Abstract |
We detected the expression and function od microRNAs (miRNAs) which might play important roles as a regulator in lens aging and cataract development. miRNA29a and miR29c may regulate the expression of related genes with posterior capsule opacity after cataract surgery and cataract development of rat lens.
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Report
(4 results)
Research Products
(14 results)
