| Project/Area Number |
20592049
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Kumamoto University |
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Principal Investigator |
FUKUSHIMA Mikiko Kumamoto University, 大学院・生命科学研究部, 准教授 (10284770)
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| Co-Investigator(Kenkyū-buntansha) |
INATANI Masaru 熊本大学, 医学部附属病院, 講師 (40335245)
GYOUTOKU Yuji 熊本大学, 医学部附属病院, 助教 (10420639)
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| Co-Investigator(Renkei-kenkyūsha) |
INOUE Toshihiro 熊本大学, 大学院・生命科学研究部, 助教 (00317025)
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| Research Collaborator |
INOUE Miyuki 熊本大学, 大学院・自然科学研究科, グローバルCOEリサーチアソシエイト
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 再生医学 / 細胞・組織 / 神経科学 |
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| Research Abstract |
The retinal tissue progenitor cell was analyzed as a basic research for the clinical application of the retina regeneration therapy. The search for the molecule was related to proliferation and differentiation of the retinal progenitor cell, and was analyzed by using the knockout mouse. Then it was clarified to the maintenance of the retinal progenitor cell of the role of the heparan sulfate proteoglycan, and relations of the molecular signal through gp130 for the differentiation.
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