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Three-dimensional analysis of dental titanium implant coated by a new biomaterial

Research Project

Project/Area Number 20592200
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionOkayama University

Principal Investigator

TAKAGI Shin  Okayama University, 大学院・医歯薬学総合研究科, 准教授 (40116471)

Co-Investigator(Kenkyū-buntansha) NAGAI Noriyuki  岡山大学, 名誉教授 (90085770)
NAGATSUKA Hitoshi  岡山大学, 大学院・医歯薬学総合研究科, 教授 (70237535)
MIZUKAWA Nobuyoshi  岡山大学, 岡山大学病院, 講師 (00263608)
TAMAMURA Ryou  岡山大学, 大学院・医歯薬学総合研究科, 助教 (00403494)
KISHIMOTO Etsuo  岡山大学, 大学院・医歯薬学総合研究科, 准教授 (20091316)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsチタン酸カルシウム / コーティング材 / インプラント / 歯科材料 / 骨結合
Research Abstract

In this study, we analyzed the effect of CaTiO3-C coating material in vitro and in vivo. Cells cultured on CaTiO3-C coated Ti plates showed good cellular proliferation and osteoblastic differentiation. Furthermore, CaTiO3-C coated implant showed satisfying bone attachment. These results suggest that CaTiO3-C plays a dominant effect on tissue response, and could be considered as a useful biomaterial for dental implants.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (17 results)

All 2010 2009 2008

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (8 results)

  • [Journal Article] Effect of CaTiO(3)-CaCO(3) prepared by alkoxide method on cell response.2010

    • Author(s)
      Rodriguez AP, Inoue M, Tanaka T, Miyake M, Sfer AM, Kishimoto E, Tsujigiwa H, Rivera RS, Nagatsuka H.
    • Journal Title

      J Biomed Mater Res A. 93(1)

      Pages: 297-303

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of a new titanium coating material (CaTiO3-aC) prepared by thermal decomposition method on osteoblastic cell response.2010

    • Author(s)
      Inoue M, Rodriguez AP, Takagi T, Katase N, Kubota M, Nagai N, Nagatsuka H, Inoue M, Nagaoka N, Takagi S, Suzuki K.
    • Journal Title

      J Biomater Appl. 24(7)

      Pages: 657-672

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of CaTiO(3)-CaCO(3) prepared by alkoxide method on cell response.2010

    • Author(s)
      Rodriguez AP
    • Journal Title

      J Biomed Mater Res A.

      Volume: 93 Pages: 297-303

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effect of calcium hydroxide removal and the influence on the sealing ability of root canals.2010

    • Author(s)
      Li Y
    • Journal Title

      J Hard Tissue Biology.

      Volume: 19 Pages: 161-166

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of a new titanium coating material(CaTiO3-aC)prepared by thermal decomposition method on osteoblastic cell response.2010

    • Author(s)
      Inoue M
    • Journal Title

      J Biomater Appl. 24

      Pages: 657-672

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 超高気孔率ハイドロキシアパタイト(アパセラムAX(R))の骨増量術への使用経験2009

    • Author(s)
      植野高章
    • Journal Title

      岡山歯学会雑誌 28

      Pages: 65-69

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemical Analysis of a Novel Coating Material, CaTiO3-aC.2008

    • Author(s)
      Okauchi-Yabuuchi M, Tamamura R, Nagaoka N, Takagi S, Kishimoto E, Takagi T, Rodriguez A, Inoue M, Nagatsuka H, Akao M, Nagai N.
    • Journal Title

      Journal of Hard Tissue Biology. 17(3)

      Pages: 115-120

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chemical Analysis of a Novel Coating Material, CaTiO_3-aC.2008

    • Author(s)
      Okauchi-Yabuuchi M
    • Journal Title

      Journal of Hard Tissue Biology 17

      Pages: 115-120

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] エナメル上皮腫の摘出術後、インプラントで咬合回復した1症例2008

    • Author(s)
      高木 慎
    • Journal Title

      岡山歯学会雑誌 27

      Pages: 115-119

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 骨髄幹細胞の歯・骨組織構成細胞への分化能についての検討2010

    • Author(s)
      辻極秀次
    • Organizer
      第52回歯科基礎医学会学術大会・総会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規コーティング材CaTiO3-aCの細胞生物学的・組織学的検討2010

    • Author(s)
      平田泰久
    • Organizer
      第19回硬組織再生生物学会総会・学術大会
    • Place of Presentation
      岡山
    • Year and Date
      2010-09-04
    • Related Report
      2010 Final Research Report
  • [Presentation] 新規コーティング材CaTiO3-aCの細胞生物学的・組織学的検討2010

    • Author(s)
      平田泰久
    • Organizer
      第19回硬組織再生生物学会・学術大会
    • Place of Presentation
      岡山
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規生体材料チタン酸カルシウム-炭酸カルシウム(CaTiO3-CaCO3)の細胞学的検討2009

    • Author(s)
      井上美穂
    • Organizer
      第51回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規コーティング材CaTiO3-aCの組織学的検討2009

    • Author(s)
      玉村亮
    • Organizer
      第18回硬組織再生生物学会総会・学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2009-09-05
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Effect of CaTiO_3-C coating by thermal decomposition method on osteoblastic cell response.2008

    • Author(s)
      M. Inoue
    • Organizer
      The 4th Internationa1 Symposium on Apatite and Correlative Biomaterials
    • Place of Presentation
      フィリピン
    • Year and Date
      2008-09-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 新規生体材料(チタン酸カルシウム-非晶質炭素複合物CaTiO3-aC)の細胞学的検討2008

    • Author(s)
      松田寛之
    • Organizer
      第17回硬組織再生生物学会総会・学術大会
    • Place of Presentation
      徳島
    • Year and Date
      2008-08-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 新規生体材料(チタン酸カルシウム-非晶質炭素複合物CaTiO_3-aC)の細胞学的検討2008

    • Author(s)
      松田寛之
    • Organizer
      第17回硬組織再生生物学会学術大会・総会
    • Place of Presentation
      徳島
    • Year and Date
      2008-08-30
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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