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Development of the diagnostic treatment of a swallowing difficulty associated with dementia, using magnetoencephalography and diffusion MRI

Research Project

Project/Area Number 20592202
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionHiroshima University

Principal Investigator

NAGASAKI Toshikazu  Hiroshima University, 医歯薬学総合研究科, 助教 (10263724)

Co-Investigator(Kenkyū-buntansha) YOSHIKAWA Mineka  広島大学, 医歯薬学総合研究科, 助教 (00444688)
TANIMOTO Keiji  広島大学, 医歯薬学総合研究科, 教授 (10116626)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords脳磁図 / 食物認知 / 指示嚥下 / 事象関連脱同期 / メタ言語 / Wernicke領域
Research Abstract

We studied cortical activity of food cognition using magnetoencephalography and tractgraphy.
Neuromagnetic activities in 14 healthy female volunteers (24-35 years old, all right-handed) were recorded while fasting. Four types of visual stimuli-food picture, non-food picture, food name, and non-food name--were presented in random order. Subjects were instructed to judge whether items were food or non-food immediately after presentation and think nothing after judgment. Cerebral activities were evaluated by visual inspection of the topographies.
Food items resulted in higher activity of beta band in the left around posterior parts of superior temporal gyrus, than did non-food items.
Visual stimulation with food judge is possibility to relate Wernicke area.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (6 results)

All 2010 2009

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (2 results)

  • [Journal Article] Development of a freeware for analysis of Nueromaginetic Epiletic discharges.2010

    • Author(s)
      A Hashizume, K Kurisu, K iida, K Arita, T Akimitsu, T Nagasaki
    • Journal Title

      Hiroshima J Med Sci 59(2)

      Pages: 21-25

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a Freeware for Analysis of Neuromagnetic Epileptic Discharges.2010

    • Author(s)
      Hashizume A., Kurisu K., IidaK., Arita K., Akimitsu K, Nagasaki T.
    • Journal Title

      Hiroshima J Med Sci

      Volume: 59 Pages: 21-25

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 食物認知における女性の大脳賦活化領域について2009

    • Author(s)
      長崎信一, 橋詰顕, 栗栖薫, 谷本啓二
    • Journal Title

      日本生体磁気学会誌 22

      Pages: 118-119

    • Related Report
      2010 Final Research Report
  • [Journal Article] 食物認知における女性の大脳賦活化領域について2009

    • Author(s)
      長崎信一, 他4人
    • Journal Title

      日本生体磁気学会誌 22

      Pages: 118-119

    • Related Report
      2009 Annual Research Report
  • [Presentation] 食物認知における女性の大脳賦活化領域について2009

    • Author(s)
      長崎信一
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      金沢市文化ホール(金沢)
    • Year and Date
      2009-05-28
    • Related Report
      2010 Final Research Report
  • [Presentation] 食物認知における女性の大脳賦活化領域について2009

    • Author(s)
      長崎信一, 他4人
    • Organizer
      第24回日本生体磁気学会大会
    • Place of Presentation
      金沢市文化ホール
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2022-01-20  

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