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Development of adhesive system with capacity of self-repair applied by Sr-CaPO4 complex

Research Project

Project/Area Number 20592227
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Conservative dentistry
Research InstitutionHiroshima University

Principal Investigator

SHIRAI Kenichi  Hiroshima University, 大学院・医歯薬学総合研究科, 助教 (20325179)

Co-Investigator(Kenkyū-buntansha) SUZUKI Shigeki  広島大学, 大学院・医歯薬学総合研究科, 助教 (30549762)
NISHIMURA Fusanori  広島大学, 大学院・医歯薬学総合研究科, 教授 (80208222)
SHIBATA Satoru  広島大学, 大学院・医歯薬学総合研究科, 助教 (20432693)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsストロンチウム / X線光電子分光分析装置 / リン酸カルシウム / 象牙質再石灰化 / 接着システム / Sr / XPS / CaPO4
Research Abstract

The aim of study is to develop adhesive system with the capacity of self-repair applied by Sr-CaPO4 complex, in order
1. to make of the best Sr-CaPO4 complex.
2. to make of experimentally adhesive system included Sr-CaPO4 complex.
3. to evaluate dentin re-calcification by Sr-CaPO4 complex and the experimental bonding system contained Sr-CaPO4 complex.
As a result, dentin re-calcification was possessed though the Sr calcium phosphate complex was not more significant than Sr and the Ca unit.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (17 results)

All 2010 2009 Other

All Journal Article (11 results) (of which Peer Reviewed: 8 results) Presentation (5 results) Remarks (1 results)

  • [Journal Article] 歯面コート材によるコーティングがもたらす歯質の脱灰抑制効果2010

    • Author(s)
      荒川真, 白井憲一, 鈴木茂樹, 本山直世, 山下明子, 峯岡茜, 藤井理史, 西村英紀
    • Journal Title

      日本歯科保存学雑誌 53

      Pages: 73-78

    • NAID

      110007880713

    • Related Report
      2010 Final Research Report
  • [Journal Article] Total bacterial counts on oral mucosa after using a commercial saliva substitute in patients undergoing hematopoietic cell transplantation2010

    • Author(s)
      Sugiura Y., Soga Y., Yamabe K., Tsutani S., Tanimoto I., Maeda H., Kokeguchi S., Fujii N., Ishimaru F., Tanimoto M., Nishimura F., Takashiba S.
    • Journal Title

      Supportive Care in Cancer 18

      Pages: 395-398

    • NAID

      120005147121

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy2010

    • Author(s)
      Cui X., Kushiyama A., Yoneda M., Nakatsu Y., Guo Y., Zhang J., Ono H., Kanna M., Sakoda H., Ono H., Kikuchi T., Fujishiro M., Shiomi M., Kamata H., Kurihara H., Kikuchi M., Kawazu S., Nishimura F., Asano T.
    • Journal Title

      Diabetes Res Clin Pract 87

      Pages: 57-63

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Extracellular heat shock protein HSP90beta secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-beta12010

    • Author(s)
      Suzuki S., Kulkarni A.B.
    • Journal Title

      Biochem Biophys Res Commun. 398(3)

      Pages: 525-531

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Decreased SIRT1 expression and LKB1 phosphorylation occur with long-term high-fat diet feeding, in addition to AMPK phosphorylation impairment in the early phase2010

    • Author(s)
      Yoneda M., Guo Y., Ono H., Nakatsu Y., Zhang J., Cui X.L., Iwashita M., Kumamoto S., Tsuchiya Y., Sakoda H., Fujishiro M., Kushiyama A., Koketsu Y., Kikuchi T., Kamata H., Nishimura F., Asano T.
    • Journal Title

      Obese Res Clin Pract 4

      Pages: 201-207

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and immunological assessment of periodontal disease in Japanese leprosy patients2010

    • Author(s)
      Ohyama H., Hongyo H., Shimizu N., Shimizu Y., Nishimura F., Nakagawa M., Arai H., Kato-Kogoe N., Terada N., Nagai A., Takashiba S., Kurihara H., Nomura Y., Murayama Y.
    • Journal Title

      Jpn J Infect Dis. 63

      Pages: 427-432

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 歯面コート材によるコーティングがもたらす歯質の脱灰抑制効果2010

    • Author(s)
      荒川真, 他8名
    • Journal Title

      日本歯科保存学雑誌

      Volume: 53 Pages: 73-78

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Synergistic Roles of Amelogenin and Ameloblastin.2009

    • Author(s)
      Hatakeyama J., Fukumoto S., Nakamura T., Haruyama N., Suzuki S., Hatakeyama Y., Shum L., Gibson C.W., Yamada Y., Kulkarni A.B.
    • Journal Title

      J.Dent.Res. 88(4)

      Pages: 318-322

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dentin sialoprotein and dentin phosphoprotein have distinct roles in dentin mineralization.2009

    • Author(s)
      Suzuki S., Sreenath T., Haruyama N., Honeycutt C., Terse A.., Cho A., Kohler T., Muller R., Goldberg M., Kulkarni A.B.
    • Journal Title

      Matrix Biol. 28(4)

      Pages: 221-229

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genetic evidence for key roles of decorin and biglycan in dentin.2009

    • Author(s)
      Haruyama N., Sreenath T.L., Suzuki S., Yao X., Wang Z., Wang Y., Honeycutt C., Iozzo R.V., Young M.F., Kulkarni A.B.
    • Journal Title

      Matrix Biol. 28(3)

      Pages: 129-136

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 新たな審美修復材料2009

    • Author(s)
      河田俊嗣, 他11名
    • Journal Title

      広島大学歯学会雑誌 41

      Pages: 121-125

    • Related Report
      2009 Annual Research Report
  • [Presentation] Prevention of LPS-induced insulin resistance in adipose tissue by ARB2010

    • Author(s)
      Iwashita M., Kumamoto S., Asano T., Nishimura F.
    • Organizer
      The 88^<th> International Association for Dental Research General Session
    • Place of Presentation
      Barcelona
    • Related Report
      2010 Final Research Report
  • [Presentation] ARB attenuates LPS-induced inflammatory cytokine expression in LDLR KO mouse2010

    • Author(s)
      Kumamoto S., Iwashita M., Asano T., Nishimura F.
    • Organizer
      The International and American Association for Dental Research
    • Place of Presentation
      Barcelona
    • Related Report
      2010 Final Research Report
  • [Presentation] Periodontal tissue destruction is associated with high triglycerides in Japanese2010

    • Author(s)
      Yamashita A., Katano M., Takagi M., Nishimura F.
    • Organizer
      The International and American Association for Dental Research
    • Place of Presentation
      Barcelona
    • Related Report
      2010 Final Research Report
  • [Presentation] Valsartan suppresses inflammatory response of LPS-induced activated macrophages and thereby improves adipose insulin resistance2010

    • Author(s)
      Iwashita M., Kumamoto S., Kushiyama A., Nakatsu Y., Tsuchiya Y., Sakoda H., Fujishiro M., Otani Y., Kikuchi T., Nishimura F., Kamata H., Asano T.
    • Organizer
      American Diabetes Association 70^<th> Scientific Sessions
    • Place of Presentation
      Orlando, Florida
    • Related Report
      2010 Final Research Report
  • [Presentation] Involvement of infiltrated macrophage in the induction of LPS-induced insulin resistance in adipose tissue and its prevention by ARB2010

    • Author(s)
      Iwashita M., Kumamoto S., Asano T., Nishimura F.
    • Organizer
      The 2^<nd> International Workshop on BioDental Education & Research
    • Place of Presentation
      Hiroshima
    • Related Report
      2010 Final Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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