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Development of a High Efficiency Algorithm for Automatic Derivation of a Interaction Using Hybrid Mathematical Model

Research Project

Project/Area Number 20700144
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Intelligent informatics
Research InstitutionWaseda University

Principal Investigator

TANAKA Kouji  Waseda University, 理工学術院, 講師 (30421225)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords質量作用則 / S-system / 数値最適化 / 遺伝的プログラミング / 遺伝的アルゴリズム / アルゴリズム / 生体生命情報学 / グリッド
Research Abstract

We proposed hybrid mathematical model which fused each advantage of Mass-action model and S-system model. Concretely, the first stage of optimization infers the outline of network structure by using S-system model and genetic algorithm as a mathematical model and optimization method, respectively. The second stage of optimization uses a result of the first stage as a constraint condition, and infers detailed network structure by using Mass-action model and genetic programming as a mathematical model and optimization method, respectively. We developed a prototype by implementing our method, and evaluated the effectiveness of our method.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (2 results)

All 2008

All Presentation (2 results)

  • [Presentation] Development and Evaluation of a Prototype System for the Inference of Genetic Networks Using Evolutionary Computation2008

    • Author(s)
      Kouji TANAKA, Hayato YAMANA
    • Organizer
      19th International Conference on Genome Informatics (GIW2008)
    • Place of Presentation
      Gold Coast, Australia.
    • Related Report
      2010 Final Research Report
  • [Presentation] Development and Evaluation of a Prototype System for the Inference of Genetic Networks Using Evolutionary Computation2008

    • Author(s)
      Kouji TANAKA and Hayato YAMANA
    • Organizer
      19th International Conference on Genome Informatics (GIW2008)
    • Place of Presentation
      Gold Coast
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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