Effects of polymorphism in genes relating Albumin synthesis on responses to endurance training

• Project/Area Number: 20700522
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Sports science
• Research Institution: Shinshu University
• Principal Investigator: OKAZAKI Kazunobu Shinshu University, 都市健康・スポーツ研究センター, 講師 (70447754)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 運動 / 遺伝子 / 血漿量 / アルブミン合成 / 体温調節能

Research Abstract

We analyzed 3 polymorphism in genes relating Albumin synthesis and found that PV was significantly different and change with training on plasma protein concentration was somewhat different between groups have different SNPs. In addition, we assessed the responses of PV and Albcont to a bout of exercise and protein-CHO ingestion and found that there was huge inter-individual variations in those variables which may be associated with albumin SNPs.

Research Products

• [Journal Article] Protein and carbohydrate supplementation increases aerobic and thermo-regulatory capacities (2009)
  • Author(s): Okazaki K, Goto M, Nose H
  • Journal Title: J Physiol 587 Pages: 5585-5590
  • Peer Reviewed
• [Journal Article] Beyond epidemiology: Field studies and the physiology laboratory as the whole world (2009)
  • Author(s): Nose H, Morikawa M, Yamazaki T, Nemoto KI, Okazaki K, Masuki S, Kamijo YI, Gen-No H
  • Journal Title: J Physiol 587 Pages: 5569-5575
  • Peer Reviewed
• [Journal Article] A new devise to estimate VO2 during incline walking by accelerometry and barometry (2009)
  • Author(s): Yamazaki T, Gen-no H, Kamijo Y, Okazaki K, Masuki S, Nose H
  • Journal Title: Med Sci Sports Exerc 41 Pages: 2213-2219
  • Peer Reviewed
• [Journal Article] Impact of protein and carbohydrate supplementation on plasma volume expansion and thermoregulatory adaptation by aerobic training in older men (2009)
  • Author(s): Okazaki K, Ichinose T, Mitono H, Chen M, Masuki S, Endoh H, Hayase H, Doi T, Nose H
  • Journal Title: J Appl Physiol 107 Pages: 725-733
  • Peer Reviewed
• [Journal Article] Protein and carbohydrate supplementation after exercise increases plasma volume and albumin content in older and young men (2009)
  • Author(s): Okazaki K, Hayase H, Ichinose T, Mitono H, Doi T, Nose H
  • Journal Title: J Appl Physiol 107 Pages: 770-779
  • Peer Reviewed
• [Journal Article] Levine BD, Menstrual cycle effects on sympathetic neural responses to upright tilt (2009)
  • Author(s): Fu Q, Okazaki K, Shibata S, Shook RP, Vangunday TB, Galbreath MM, Reelick MF
  • Journal Title: J Physiol 587 Pages: 2019-2031
  • Peer Reviewed
• [Journal Article] 3年間のインターバル速歩トレーニングによる中高年の体力および生活習慣病指標への影響 (2009)
  • Author(s): 田邊愛子, 岡崎和伸, 山崎敏明, 森川真悠子, 宮川健, 源野広和, 根本賢一, 能勢博
  • Journal Title: 長野体育学研究 16 Pages: 13-21
  • Peer Reviewed
• [Journal Article] Protein and carbohydrate supplementation increases aerobic and thermo-regulatory capacities (2009)
  • Author(s): Okazaki K, Goto M, Nose H
  • Journal Title: Journal of Physiology 587 Pages: 5585-5590
  • Peer Reviewed
• [Journal Article] Beyond epidemiology : Field studies and the physiology laboratory as the whole world (2009)
  • Author(s): Nose H, Morikawa M, Yamazaki T, Nemoto KI, Okazaki K, Masuki S, Kamijo YI, Gen-No H
  • Journal Title: Journal of Physiology 587 Pages: 5569-5575
  • Peer Reviewed
• [Journal Article] Impact of protein and carbohydrate supplementation on plasma volume expansion and thermoregulatory adaptation by aerobic training in older men (2009)
  • Author(s): Okazaki K, Ichinose T, Mitono H, Chen M, Masuki S, Endoh H, Hayase H, Doi T, Nose H
  • Journal Title: Journal of Applied Physiology 107 Pages: 725-733
  • Peer Reviewed
• [Journal Article] Protein and carbohydrate supplementation after exercise increases plasma volume and albumin content in older and young men (2009)
  • Author(s): Okazaki K, Hayase H, Ichinose T, Mitono H, Doi T, Nose H
  • Journal Title: Journal of Applied Physiology 107 Pages: 770-773
  • Peer Reviewed
• [Journal Article] Menstrual cycle effects on sympathetic neural responses to upright tilt (2009)
  • Author(s): Fu Q, Okazaki K, Shibata S, Shook RP, Vangunday TB, Galbreath MM, Reelick MF, Levine BD
  • Journal Title: Journal of Physiology 587 Pages: 2019-2031
  • Peer Reviewed
• [Journal Article] 3年間のインターバル速歩トレーニングによる中高年の体力および生活習慣病指標への効果 (2009)
  • Author(s): 田邊愛子
  • Journal Title: 長野体育学研究 16 Pages: 13-21
  • Peer Reviewed
• [Journal Article] A new devise to estimate VO2 during incline walking by accelerometry and barometry (2009)
  • Author(s): Yamazaki T
  • Journal Title: Medicine & Science in Sports & Exercise (印刷中)
  • Peer Reviewed
• [Journal Article] 体液・体温調節のための機能性食品 (2008)
  • Author(s): 岡崎和伸, 能勢博
  • Journal Title: Functional Food 2 Pages: 275-281
• [Journal Article] 体液・体温調節のための機能性食品 (2008)
  • Author(s): 岡崎和伸
  • Journal Title: Functional Food 2(3) Pages: 275-281
• [Journal Article] Effects of a 3-month high-intensity interval walking training on physical fitness and cardiovascular risk factors in middle-aged individuals
  • Author(s): Lalande S, Okazaki K, Yamazaki T, Nose H, Warren BA, Olsen KD, Joyner MJ, Johnson BD
  • Journal Title: Journal of Primary Care & Community Health (印刷中)
  • Peer Reviewed
• [Journal Article] Physical fitness and indices of lifestyle-related diseases before and after interval walking training in middle-aged and older males and females
  • Author(s): Morikawa M, Okazaki K, Masuki S, Kamijo YI, Yamazaki T, Gen-No H, Nose H
  • Journal Title: Br J Sports Med (印刷中)
  • Peer Reviewed
• [Presentation] GABAが暑熱下安静時の温度感覚に及ぼす影響 (2009)
  • Author(s): 宮澤太機, 河端隆志, 岡崎和伸, 鈴木崇士, 今井大喜, 濱本健, 進藤麻帆, 鈴木明菜, 松村新也, 宮側敏明
  • Organizer: 第64回日本体力医学会大会
  • Place of Presentation: 新潟
  • Year and Date: 2009-09-20
• [Presentation] 1.3気圧環境が体温および末梢・中心循環におよぼす影響 (2009)
  • Author(s): 鈴木明菜, 岡崎和伸, 今井大喜, 官澤太機, 濱本健, 進藤麻帆, 松村新也, 河端隆志, 宮側敏明
  • Organizer: 第64回日本体力医学会大会
  • Place of Presentation: 新潟
  • Year and Date: 2009-09-19
• [Presentation] Post-exercise protein and cardohydrate supplementation enhances training adaptations on skeletal muscle and cardiovascular function by interval walking training in the elderly (2009)
  • Author(s): Okazaki K, Yazawa D, Goto M, Kamijo YI, Gon-no H, Hamada K, Nose H
  • Organizer: Exercise, Gene, Preventive Medicine Meeting
  • Place of Presentation: Karuizawa
  • Year and Date: 2009-08-03
• [Presentation] Protein and CHO supplementation increases aerobic and thermo-regulatory capacities. (2009)
  • Author(s): Okazaki K, Nose H, Goto M
  • Organizer: The 36th Congress of the International Union of Physiological Sciences
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-31
• [Presentation] Protein and CHO supplementation increases aerobic and thermo-regulat ory capacities (2009)
  • Author(s): Okazaki K, Nose H, Goto M
  • Organizer: The 36th Congress of the International Union of Physiological Sciences(IUPS)
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-30
• [Presentation] Enhanced skin blood flow response to hyperthermia after endurance training is mainly caused by plasma volume expansion in humans (2009)
  • Author(s): Ikegawa S, Kamijo YI, Okazaki K, Masuki S, Okada Y, Nose H
  • Organizer: The 36th Congress of the International Union of Physiological Sciences
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-29
• [Presentation] Rapid plasma volume restoration enhances skin vasodilation but not sweat rate in hypovolemic and passively warmed men (2009)
  • Author(s): Kamijo YI, Okazaki K, Ikegawa S, Okada Y, Nose H
  • Organizer: The 36th Congress of the International Union of Physiological Sciences
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-29
• [Presentation] Symapathetic vasoconstrictor responsiveness is reduced by 5-day endurance training with enhanced baroreflex sensitivity in men (2009)
  • Author(s): Okazaki K, Kamijo YI, Masuki S, Ikegawa S, Okada Y, Yazawa D, Hata T, Shiba Y, Takahashi M, Ikeda U, Nose H
  • Organizer: The 36th Congress of the International Union of Physiological Sciences
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-29
• [Presentation] Enhanced skin blood flow response to hyperthermia after endurance training is mainly caused by plasma volume expansion in humans (2009)
  • Author(s): Ikegawa S, Kamijo YI, Okazaki K, Masuki S, Okada Y, Nose H
  • Organizer: The 36th Congress of the International Union of Physiological Sciences(IUPS)
  • Place of Presentation: Kyota
  • Year and Date: 2009-07-28
• [Presentation] Symapathetic vasoconstrictor responsiveness is reduced by 5-day endursnce training with enhanced baroreflex sensitivity in men (2009)
  • Author(s): Okazaki K, Kamijo YI, Masuki S, Ikegawa S, Okada Y, Yazawa D, Hata T, Shiba Y, Takahashi M, Ikeda U, Nose H
  • Organizer: The 36th Congress of the International Union of Physiological Sciences(IUPS)
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-28
• [Presentation] 中高年・インターバル速歩トレーニング効果の初期身体特性と速歩量の差違 (2008)
  • Author(s): 森川真悠子, 岡崎和伸, 山崎敏明, 源野広和, 能勢博
  • Organizer: 第63回日本体力医学会大会
  • Place of Presentation: 別府
  • Year and Date: 2008-09-19
• [Presentation] 中高年における3年間のインターバル速歩トレーニング効果 (2008)
  • Author(s): 田邊愛子、岡崎和伸、山崎敏明、源野広和、能勢博
  • Organizer: 第63回日本体力医学会大会
  • Place of Presentation: 別府
  • Year and Date: 2008-09-19
• [Presentation] 中高年・インターバル速歩トレーニング効果の初期身体特性と速歩量の差違 (2008)
  • Author(s): 森川真悠子
  • Organizer: 第63回日本体力医学会総会
  • Place of Presentation: 別府
  • Year and Date: 2008-09-19
• [Presentation] 中高年における3年間のインターバル速歩トレーニング効果 (2008)
  • Author(s): 田邊愛子
  • Organizer: 第63回日本体力医学会総会
  • Place of Presentation: 別府
  • Year and Date: 2008-09-19
• [Presentation] 中高年における4ヶ月間のインターバル速歩トレーニングによる初期属性別効果の違い (2008)
  • Author(s): 森川真悠子、岡崎和伸、山崎敏明、源野広和、能勢博
  • Organizer: 第31回日本基礎老化学会大会
  • Place of Presentation: 松本
  • Year and Date: 2008-06-13
• [Presentation] 中高年における3年間のインターバル速歩トレーニングが生活習慣病指標・体力維持・改善に与える効果 (2008)
  • Author(s): 田邊愛子
  • Organizer: 第31回日本基礎老化学会大会
  • Place of Presentation: 松本
  • Year and Date: 2008-06-12
• [Book] からだと温度の事典 (2010)
  • Author(s): 岡崎和伸, 能勢博
  • Total Pages: 640
  • Publisher: 朝倉書店
• [Book] 浸透圧・容量調節系関連と高齢者の特徴:Section 13トレーニングと体液、身体トレーニング (2009)
  • Author(s): 岡崎和伸、能勢博
  • Publisher: 真興交易医書出版部
• [Book] 加齢と体温調節、からだと温度の事典 (2009)
  • Author(s): 岡崎和伸、能勢博
  • Publisher: 朝倉書店
• [Book] 浸透圧・容量調節系関連と高齢者の特徴 : Section 13トレーニングと体液 : 身体トレーニング運動生理学から見た身体機能の維持・向上 (2009)
  • Author(s): 岡崎和伸
  • Publisher: 真興交易医書出版部
• [Patent(Industrial Property Rights)] 血漿量増加促進剤 (2008)
  • Inventor(s): 岡崎和伸、早瀬秀樹、土居達也、能勢博
  • Industrial Property Rights Holder: 国立大学法人信州大学、大塚製薬株式会社
  • Acquisition Date: 2008-07-04