Role of circadian clock in regulation of metabolic syndrome onset by food factor
Project/Area Number |
20700595
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Eating habits, studies on eating habits
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Research Institution | Osaka City University |
Principal Investigator |
FUKUMURA Tomoe Osaka City University, 大学院・生活科学研究科, 講師 (80336792)
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Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 健康と食生活 / 食品因子 / メタボリック症候群 / 体内時計 |
Research Abstract |
The aim of the present study was to examine the molecular mechanism of the metabolic syndrome onset by the disruption of circadian clock. Experiments were carried out on metabolic syndrome model rats under various conditions. As a result, there were significant difference in some clock gene expression between control and metabolic syndrome model rats. These findings suggest the possibility that these genes regulate onset of metabolic syndrome.
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Report
(4 results)
Research Products
(18 results)
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[Journal Article] The low-density lipoprotein receptor-related protein 10 is a negative regulator of the canonical Wnt/b-catenin signaling pathway.2010
Author(s)
YH Jeong, M Sekiya, M Hirata, M Ye, A Yamagishi, SM Lee, MJ Kang, A Hosoda, T Fukumura, DH Kim, S Saeki.
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Journal Title
Biochemical and Biophysical Research Communications Vol.392
Pages: 495-499
Related Report
Peer Reviewed
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[Journal Article] Molecular charact erization and expression of the low-density lipoprotein receptor-related protein-102010
Author(s)
YH Jeong, K Ishikawa, Y Someya, A Hos oda, T Yoshimi, C Yokoyama, S Liryu-seo, MJ Kang, T tachibana, H Kiyama, T Fukum ura, DH Kim, S Saeki.
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Journal Title
a new member of the LDLR gene family Biochemical and Biophysical Research Communications Vol.391
Pages: 1110-1115
Related Report
Peer Reviewed
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