Research Project
Grant-in-Aid for Young Scientists (B)
This work is targeting to produce a single oocyte or donor cell laden droplet on a chip by means of droplet dispensing techniques. The novelty of the present work is that we produce particle-laden droplet by using magnetic micro-actuator (MMT) to achieve the fusion of the oocyte and donor cell on a chip. The main achievement of the work is summarized as follows :(1) Valve-functioned MMT was successfully chopped droplet and produced size-controlled droplet together with enclosing a particle whose size of 50 μm and transported them one by one. Therefore a wide range of the size of particles or cells can be enclosed in a droplet on a chip.(2) Hybrid type MMT was successfully fabricated by using high-accuracy Ni metal by electroplating technique. Local rigidity and magnetic property of MMT was successfully controlled and obtained 6 times displacement as large as conventional setting. The revised design chip could have laminar sheath flow or pressure balance which provided on-demand droplet production on a chip successfully.
All 2010 2009 2008 Other
All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (14 results) Remarks (3 results)
Advanced Robotics (Accepted)
International Journal of Automation and Technology Vol.3,No.5
Pages: 502-508
Journal of Robotics and Mechatronics Vol.21,No.2
Pages: 229-235
International Journal of Automation and Technology 3
Journal of Robotics and Mechatronics 21(in press)
http://www.biorobotics.mech.nagoya-u.ac.jp/
http://www.imech.mech.tohoku.ac.jp/research/research.html
