Association between ebony gene polymorphism and mate preference in Drosophila

• Project/Area Number: 20770007
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Genetics/Genome dynamics
• Research Institution: National Institute of Genetics
• Principal Investigator: TAKAHASHI Aya National Institute of Genetics, 集団遺伝研究系, 助教 (90370121)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 種分化 / ebony / 昆虫 / 多型 / 上流解析 / 多面発現 / 交尾行動 / ショウジョウバエ

Research Abstract

The goal of this project is to study the association between mate preference and polymorphism in the 5' cis-regulatory region of the ebony gene in Drosophila. The gene codes for an enzyme in the melanin synthesis pathway and is also known to function in the nervous system. Natural variation in the 5' cis-regulatory region was shown to be responsible for the expression level variation in epidermis as well as that in brain. The expression level variation in brain was shown to influence the mating behavior. Therefore, the results indicated that the variation in 5' cis-regulatory region affects mate preference in this species.

Research Products

• [Journal Article] Introgression of Drosophila simulans Nup160 (nuclear pore protein 160) in Drosophila melanogaster alone does not cause inviability but does cause female sterility. (2010)
  • Author(s): Sawamura, K., Maehara, K., Mash ino, S., Kagesawa, T., Kajiwara, M., Matsuno, K., Takahashi, A., Takano-Shimizu, T.
  • Journal Title: Genetics 186 Pages: 669-676
  • Peer Reviewed
• [Journal Article] Introgression of Drosophila simulans Nup160 (nuclear pore protein 160) in Drosophila melanogaster alone does not cause inviability but does cause female sterility. (2010)
  • Author(s): Sawamura, et al.
  • Journal Title: Genetics Volume: 186 Pages: 669-676
  • Peer Reviewed
• [Journal Article] Effect of splicing regulation on the synonymous codon usage in alternatively spliced exons of Drosophila Dscam. (2009)
  • Author(s): Takahashi, A.
  • Journal Title: BMC Evol.Biol. 9 Pages: 214-214
  • Peer Reviewed
• [Journal Article] Characteristics of genes up-regulated and down-regulated after 24 h starvation in the head of Drosophila. (2009)
  • Author(s): Fujikawa, K., Takahashi, A., Nishimura, A., Itch, M., Toshiyuki Takano-Shimizu, T., Ozaki, M.
  • Journal Title: Gene 446 Pages: 11-17
  • Peer Reviewed
• [Journal Article] Molecular spectrum of spontaneous denova mutations in male and female germ line cells of Drosophila melanogaster. (2009)
  • Author(s): Watanabe, Y., Takahashi, A., Itch, M., Takano-Shimizu, T.
  • Journal Title: Genetics 181 Pages: 1035-1043
  • Peer Reviewed
• [Journal Article] 中立説と実験集団遺伝学 (2009)
  • Author(s): 高橋文
  • Journal Title: 総研大ジャーナル No.15 Pages: 11-13
• [Journal Article] Effect of splicing regulation on the synonymous codon usage in alternatively spliced exons of Drosopbila Dscam (2009)
  • Author(s): Takahashi, A.
  • Journal Title: BMC Evol.Biol. 9 Pages: 214-214
  • Peer Reviewed
• [Journal Article] Characteristics of genes up-regulated and down-regulated after 24h starvation in the head of Drosophila (2009)
  • Author(s): Fujikawa et al.
  • Journal Title: Gene 446 Pages: 11-17
  • Peer Reviewed
• [Journal Article] Molecular spectrum of spontaneous de novo mutations in male and female germline cells of Drosophila melanogaster (2009)
  • Author(s): Watanabe, et.al.
  • Journal Title: Genetics 181 Pages: 1035-1043
  • Peer Reviewed
• [Journal Article] Mosaic genealogy of the Mus musculus genome revealed by 21 nuclear genes from its three subspecies. (2008)
  • Author(s): Liu, Y.-H., Takahashi, A., Kitano, T., Koide, T., Shiroishi, T., Moriwaki, K., Saitou, N.
  • Journal Title: Genes Genet.Syst. 83 Pages: 77-88
  • NAID: 10024395628
  • Peer Reviewed
• [Presentation] ショウジョウバエにおける体色と行動の関連性について (2010)
  • Author(s): 高橋文
  • Organizer: 北海道大学低温科学研究所研究集会
  • Place of Presentation: 北海道大学(札幌市)
  • Year and Date: 2010-09-22
• [Presentation] ショウジョウバエにおける体色と行動の関連性について (2010)
  • Author(s): 高橋文
  • Organizer: 北海道大学低温科学研究所研究集会「ショウジョウバエ研究のいまとこれから-特に,キイロショウジョウバエ以外の研究に注目して-」
  • Place of Presentation: 北海道大学(札幌市)
  • Year and Date: 2010-09-22
• [Presentation] ショウジョウバエにおける体色種内変異の分子基盤と行動への影響について (2010)
  • Author(s): 高橋文
  • Organizer: 第82回遺伝学会WS
  • Place of Presentation: 北海道大学(札幌市)
  • Year and Date: 2010-09-20
• [Presentation] ショウジョウバエにおける体色種内変異の分子基盤と行動への影響について (2010)
  • Author(s): 高橋文
  • Organizer: 第82回遺伝学会WS「ゲノム間の軋轢と調和が生物多様性を生みだす細胞機構」
  • Place of Presentation: 北海道大学(札幌市)
  • Year and Date: 2010-09-20
• [Presentation] ショウジョウバエにおける体色の種内変異と非ランダム交配 (2010)
  • Author(s): 高橋文
  • Organizer: 特定領域研究『植物ゲノム障壁』若手ワークショソプ
  • Place of Presentation: 名古屋大学(名古屋市)
  • Year and Date: 2010-07-12
• [Presentation] ショウジョウバエにおける体色の種内変異と非ランダム交配 (2010)
  • Author(s): 高橋文
  • Organizer: 特定領域研究『植物ゲノム障壁』若手ワークショップ
  • Place of Presentation: 名古屋大学(名古屋市)
  • Year and Date: 2010-07-12
• [Presentation] キイロショウジョウバエ集団内における胸部三叉の色素沈着パターンの多型と非ランダム交配 (2009)
  • Author(s): 高橋文, ら
  • Organizer: 日本遺伝学会第81回大会
  • Place of Presentation: 信州大学(松本市)
  • Year and Date: 2009-09-18
• [Presentation] キイロショウジョウバエ集団内における胸部三叉の色素沈着パターンの多型と非ランダム交配 (2009)
  • Author(s): 高橋文, ら
  • Organizer: 日本遺伝学会第81回大会
  • Place of Presentation: 松本市
  • Year and Date: 2009-09-18
• [Presentation] Natural variant of a pigmentation gene and its role in mating incompatibility (2009)
  • Author(s): Takahashi, et al.
  • Organizer: The 9^<th> Japanese Drosophila Research Conference
  • Place of Presentation: ヤマハリゾート(掛川市)
  • Year and Date: 2009-07-07
• [Presentation] Natural variant of a pigmentation gene and its role in mating incompatibility (2009)
  • Author(s): Takahashi et al.
  • Organizer: The 9^<th> Japanese Drosophila Research Conference
  • Place of Presentation: 掛川市
  • Year and Date: 2009-07-07
• [Presentation] Dscam遺伝子のaltematively spliced exonにおけるスプライシングの制御が同義コドン使用頻度に与える影響の解析 (2008)
  • Author(s): 高橋文,ら
  • Organizer: 日本遺伝学会第80回大会
  • Place of Presentation: 名古屋大学(名古屋市)
  • Year and Date: 2008-09-04
• [Presentation] Dscam遺伝子のalternatively spliced exonにおけるスプライシングの制御が同義コドン使用頻度に与える影響の解析 (2008)
  • Author(s): 高橋文ら
  • Organizer: 日本遺伝学会第80回大会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-09-04
• [Presentation] ショウジョウバエ模様の種内多型について (2008)
  • Author(s): 高橋文
  • Organizer: 第10回日本進化学会大会
  • Place of Presentation: 東京大学(東京都)
  • Year and Date: 2008-08-23
• [Presentation] ショウジョウバエ模様の種内多型について (2008)
  • Author(s): 高橋文
  • Organizer: 第10回日本進化学会大会
  • Place of Presentation: 東京
  • Year and Date: 2008-08-23
• [Book] シリーズ現代の生態学(「生殖隔離と種分化遺伝子」)(7巻4部4章) (2011)
  • Author(s): 高橋文
  • Publisher: 共立出版(in press)
• [Remarks] ホームページ等
  • URL: http://www.nig.ac.jp/section/takano/takano-j.html
• [Remarks]
  • URL: http://www.nig.ac.jp/section/takano/takano-j.html