| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
We try the identification of the undifferentiated hematopoietic cells on mouse embryos. In the AGM regions, which show the emergence of cells containing the long-term repopulating activity in irradiated adult mice, CD45lowc-Kithigh cells had the highest ability to form hematopoietic cell colonies in vitro. We found that CD45lowc-Kithigh cells were identified in the stages of showing hematopoiesis in the AGM regions. The CD45lowc-Kithigh cells were also identified in yolk san and fetal liver. In the placenta, the hematopoietic activity of CD45highc-Kithigh cells was highest.
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