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Analysis of defense system regulated by interferon-induced GTP binding proteins

Research Project

Project/Area Number 20780208
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Basic veterinary science/Basic zootechnical science
Research InstitutionTottori University

Principal Investigator

ASANO Atsushi  Tottori University, 農学部, 准教授 (90312404)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords地域日本語教室 / 日本語学習支援 / 外国人支援者 / ニワトリ / インターフェロン / IFN誘導性GTP結合蛋白質群 / IFN誘導性GTP結合蛋白群
Research Abstract

Interferon (IFN)-induced GTP binding proteins (GBPs) were thought to play a part in inhibition of amplification of infected viruses in animal. I identified two novel GBP genes, GBP2 and GBP3, of the chicken. The mRNA of these genes was induced by various IFNs such as IFNβ, IFNγ and IFNλ. Chicken GBP2 protein was located in the cytoplasm, which is similar to Mx, one of the antiviral GTP binding protein. Chicken GBP2 has the highest homology to human GBP1, which is an antiviral GBP, suggesting its antiviral property.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (4 results)

All 2009 2008

All Presentation (4 results)

  • [Presentation] 組換えニワトリインターフェロンλタンパク質の抗ウイルス遺伝子誘導作用2009

    • Author(s)
      増田康充、浅野淳、山野好章
    • Organizer
      第148回日本獣医学会
    • Place of Presentation
      鳥取
    • Year and Date
      2009-09-25
    • Related Report
      2009 Final Research Report
  • [Presentation] 組換えニワトリインターフェロンλタンパク質の抗ウイルス遺伝子誘導作用2009

    • Author(s)
      増田康充
    • Organizer
      第148回日本獣医学会
    • Place of Presentation
      鳥取市・とりぎん文化会館
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 組換えニワトリインターフェロンλタンパク質の精製2008

    • Author(s)
      増田康充、浅野淳、神尾高志、北村直樹、澁谷泉、山野好章
    • Organizer
      第146回日本獣医学会
    • Place of Presentation
      宮崎
    • Year and Date
      2008-09-24
    • Related Report
      2009 Final Research Report
  • [Presentation] 組換えニワトリインターフェロンλタンパク質の精製2008

    • Author(s)
      増田康充
    • Organizer
      第146回日本獣医学会
    • Place of Presentation
      ワールドコンベンションセンター(宮崎)
    • Year and Date
      2008-09-24
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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