Analysis of defense system regulated by interferon-induced GTP binding proteins
| Project/Area Number |
20780208
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Tottori University |
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Principal Investigator |
ASANO Atsushi Tottori University, 農学部, 准教授 (90312404)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 地域日本語教室 / 日本語学習支援 / 外国人支援者 / ニワトリ / インターフェロン / IFN誘導性GTP結合蛋白質群 / IFN誘導性GTP結合蛋白群 |
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| Research Abstract |
Interferon (IFN)-induced GTP binding proteins (GBPs) were thought to play a part in inhibition of amplification of infected viruses in animal. I identified two novel GBP genes, GBP2 and GBP3, of the chicken. The mRNA of these genes was induced by various IFNs such as IFNβ, IFNγ and IFNλ. Chicken GBP2 protein was located in the cytoplasm, which is similar to Mx, one of the antiviral GTP binding protein. Chicken GBP2 has the highest homology to human GBP1, which is an antiviral GBP, suggesting its antiviral property.
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Report
(3 results)
Research Products
(4 results)
