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Characterization of novel regulatory system for the bacteriocin biosynthesis

Research Project

Project/Area Number 20790065
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biological pharmacy
Research InstitutionHiroshima University

Principal Investigator

NODA Masafumi  Hiroshima University, 大学院・医歯薬学総合研究科, 寄附講座助教 (40457289)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords微生物 / 発現制御 / バイオテクノロジー
Research Abstract

In the present study, a part of the particular bacteriocin biosynthesis regulatory system for brevicin 174A produced by plant-derived lactic acid bacteria was elucidated, and novel bacteriocin immunity protein was determined from the biosynthesis gene cluster.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (8 results)

All 2010 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (6 results)

  • [Journal Article] Characterization of four plasmids harboured in a Lactobacillus brevis strain encoding a novel bacteriocin, brevicin 925A, and construction of a shuttle vector for lactic acid bacteria and Escherichia coli2009

    • Author(s)
      Wada, T., Noda, M., Kashiwabara, F., Jeon, H. -J., Shirakawa, A., Yabu, H., Matoba, Y., Kumagai, T, Sugiyama, M
    • Journal Title

      Microbiology 155

      Pages: 1726-1737

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of four plasmids harbored in a Lactobacillus brevis strain encoding a novel bacteriocin, brevicin 925A, and construction of a shuttle vector for lactic acid bacteria and Escherichia coli2009

    • Author(s)
      Wada, T., et.al.
    • Journal Title

      Microbiology (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 植物乳酸菌Lactobacillus brevis 174Aの産生する新奇バクテリオシン2010

    • Author(s)
      野田正文, 松尾隆広, 的場康幸, 熊谷孝則, 杉山政則
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Related Report
      2009 Final Research Report
  • [Presentation] 植物乳酸菌Lactobacillus brevis 174Aの産生する新奇バクテリオシン2010

    • Author(s)
      野田正文
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山県岡山市
    • Related Report
      2009 Annual Research Report
  • [Presentation] クラスIIbバクテリオシンbrevicin 174Aの産生制御の分子機構解明2009

    • Author(s)
      古林泰子, 野田正文, 柏原ふみ, 松尾隆広, 全亨濬, 的場康幸, 熊谷孝則, 杉山政則
    • Organizer
      第61回日本生物工学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2009 Final Research Report
  • [Presentation] バクテリオシン生産性植物乳酸菌925A株の保有する4種類のプラスミドの構造と機能2009

    • Author(s)
      野田正文, 和田貴臣, 全亨濬, 柏原ふみ, 的場康幸, 熊谷孝則, 杉山政則
    • Organizer
      日本乳酸菌学会2009年度大会
    • Place of Presentation
      山梨
    • Related Report
      2009 Final Research Report
  • [Presentation] バクテリオシン生産性植物乳酸菌925A株の保有する4種類のプラスミドの構造と機能2009

    • Author(s)
      野田正文
    • Organizer
      日本乳酸菌学会2009年度大会
    • Place of Presentation
      山梨県甲府市
    • Related Report
      2009 Annual Research Report
  • [Presentation] クラスIIbバクテリオシンbrevicin 174Aの産生制御の分子機構解明2009

    • Author(s)
      古林泰子
    • Organizer
      第61回日本生物工学会大会
    • Place of Presentation
      愛知県名古屋市
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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