Development of biomarker for diagnosis of metabolic syndrome

• Project/Area Number: 20790456
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Public health/Health science
• Research Institution: Research Institute, International Medical Center of Japan
• Principal Investigator: MATSUSHITA Yumi Research Institute, International Medical Center of Japan, 国際保健医療研究部, 国際疫学研究室長 (50450599)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: メタボリックシンドローム / 国際保健学 / 国際情報交換 / ベトナム

Research Abstract

According to the ROC curve, an optimal cutoff value for waist circumference to detect multiple risk factors was 82cm in men and 73cm in women in Hanoi, and 76cm in men and 73cm in women in Thai Binh, yielding the maximal sensitivity plus specificity, and these values were different by the area in Vietnam. Furthermore, we examined the detective ability of adiponectin for diagnosis of metabolic syndrome. The same ability was shown in both areas.

Research Products

• [Journal Article] Awareness of the risk factors for diabetes and hypertension among the Vietnamese and Japanese populations.
  • Author(s): Kishimoto M, Thai SP, Kajio H, Ngoc QN, Matsushita Y, Huyen QD, Kanagawa S, Hong HPT, Takahashi Y, Thi HN, Noda M, Thuy HT, Phuong TPT, Doan LD, Lan VN
  • Journal Title: ASEAN HEART J. 17 Pages: 7-12
• [Presentation] The cutoff level of waist circumference for predicting the presence of multiple risk factors for cardiovascular disease in the Vietnamese population. (2009)
  • Author(s): Matsushita Y, Thai SP, Kajio H, Ngoc QN, Kishimoto M, Kanagawa S, Hong HPT, Takahashi Y, Noda M, Thuy HT, Doan LD, Lan VN
  • Organizer: 20th World Diabetes Congress
  • Place of Presentation: Montreal Convention Centre, Montreal, Canada
  • Year and Date: 2009-10-19
• [Presentation] The cutoff level of waist circumference for predicting the presence of multiple risk factors for cardiovascular disease in the Vietnamese population. (2009)
  • Author(s): Yumi Matsushita (presenter), Son Pham Thai, Hiroshi Kajio, Quang Nguyen Ngoc, Miyako Kishimoto, Shuzo Kanagawa, Hoa Pham Thi Hong, Yoshihiko Takahashi, Mitsuhiko Noda, Hanh Tran Thuy, Loi Do Doan, Viet Nguyen Lan.
  • Organizer: 20^<th> World Diabetes Congress
  • Place of Presentation: Montreal Convention Centre, Montreal, Canada
  • Year and Date: 2009-10-19
• [Presentation] The cutoff level of waist circumference yielding the maximal sensitivity plus specificity for predicting the presence of multiple risk factors for cardiovascular in the Vietnamese population. (2008)
  • Author(s): Matsushita Y, Kishimoto M, Kanagawa S, Takahashi T, Noda M, Kajio H, Thai SP, Ngoc NQ, Thu HN, Doan LD, Lan VN, Gia KP
  • Organizer: 17th ASEAN Congress of Cardiology
  • Place of Presentation: National Convention Center, Hanoi, Vietnam
• [Presentation] Knowledge about the risk factors of diabetes and hypertension among the Vietnamese and Japanese communities and outpatients. (2008)
  • Author(s): Kishimoto M, Kajio H, Matsushita Y, Kanagawa S, Takahashi Y, Noda M, Thai SP, Ngoc QN, Hong HPT, Doan LD
  • Organizer: 17th ASEAN Congress of Cardiology
  • Place of Presentation: National Convention Center, Hanoi, Vietnam