The role of circulating fibrocytes for cardiovascular remodeling

• Project/Area Number: 20790540
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Circulatory organs internal medicine
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: AMANO Katsuya Kyoto Prefectural University of Medicine, 医学部, 博士研究員 (70468263)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 分子血管病態学 / 心筋線維化

Research Abstract

The human peripheral blood contains fibrocytes that can differentiate into other mesenchymal cells, such as myofibroblasts and adipocytes . In this study, we examined the role of fibrocytes in cardiovascular disease. We suggest that fibrocytes are not the critical role in cardiovascular disease such as infracted myocardium, over pressure load and ischemic limb disease in a mouse model.

Research Products

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  • URL: http://www.f.kpu-m.ac.jp/k/med2/