Analysis of the susceptibility gene for severe pneumonia with S.pneumoniae
Project/Area Number |
20790577
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Respiratory organ internal medicine
|
Research Institution | Toho University |
Principal Investigator |
KIMURA Soichiro Toho University, 医学部, 助教 (60408870)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 肺炎球菌 / Genotype / 肺炎 / マウス / Genotyping |
Research Abstract |
I explored the disease-susceptible genes associated with severe pneumonia with Streptococcus pneumoniae in mouse model. I identified candidate region within 10cM on chromosome 1 by using linkage analysis with CBA/J x C57B6/J F(2) intercross mouse. In this region, I confirmed possible disease-susceptibility-related genes such as immunoglobulin and apoptosis.
|
Report
(4 results)
Research Products
(2 results)