Structure of Sebosomes, secret membrane vesicles of sebocytes
| Project/Area Number |
20790804
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dermatology
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| Research Institution | Ehime University |
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Principal Investigator |
NAGAI Ayako Ehime University, 医学部附属病院, 助教(特定教員) (90420562)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | セボゾーム / 脂腺細胞 / ヒストン / 抗菌 / 分泌膜小胞 / Sebosomes / Sebocytes / 脂線細胞 / 脂質ラフト |
|---|
| Research Abstract |
Rat cultured sebocytes synthesized and secreted Sebosomes. It was suggested that Sebosomes contain various subcellular organelles. Recycling endosomes were involved in distribution and localization of the organelles to form the complex membrane system of Sebosomes. Early and late endosomes, lysosomes, lipid granules and lipid rafts were included in the system, in addition to de nove synthesized proteins.
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Report
(4 results)
Research Products
(9 results)
