Development of radiometal-octabromoporphyrin complex as a new radiopharmaceuticals for cancer
| Project/Area Number |
20790898
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Okayama University |
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Principal Investigator |
KITAMURA Yoji Okayama University, 学際科学実験センター, 准教授 (10368483)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 放射性医薬品 / ポルフィリン / 腫瘍 / 錯体 / 八臭素化 |
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| Research Abstract |
This study aims to develop radiometal-octabromoporphyrin complex as a new radiopharmaceuticals for cancer. OBTMPyP and OBTCPP were synthesized as a cationic compound, and as an anionic compound respectively. It is found that OBTCPP make complex with 65Zn at a room temperature.
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Report
(3 results)
Research Products
(19 results)
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[Presentation] 糖尿病治療薬剤としてのZn-DTS錯体の開発2010
Author(s)
門脇沙緒莉1, 巽朝菜1, 神野伸一郎1, 中島聡1, 北村陽二2, 廣村信3, 御舩正樹1, 吉川豊4, 佐治英 郎5, 榎本秀一1
Organizer
日本薬学会第130年会
Place of Presentation
岡山県総合グラウンド体育館(岡山
Year and Date
2010-03-30
Related Report
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[Presentation] 経口糖尿病治療薬としてのZn-DTS錯体の開発2010
Author(s)
神野伸一郎1, 中島聡1, 御舩正 樹1, 吉川豊4, 佐治英郎5, 榎本秀 一1, 3
Organizer
第8回次世代を担う若手のためのフィジカル・ファーマフォーラム
Place of Presentation
岡山大学五十周年記念館(岡山)
Year and Date
2010-03-26
Related Report
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[Presentation] N末アミノ酸を置換した111In-DOTA結合octreotide誘導体の腎放射能集積に関する検討2008
Author(s)
北村陽二, 秋澤宏行, 八木美知枝, 清水隆也, 中島聡, 秋吉佑美, 御舩正樹, 斎藤寛, 荒野泰, 榎本秀一, 佐治英郎
Organizer
第1回メタロミクス研究フォーラム
Place of Presentation
昭和女子大学学園本部館(東京)
Year and Date
2008-11-28
Related Report
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