| Project/Area Number |
20791135
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Chiba University |
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Principal Investigator |
TATE Shinichi Chiba University, 大学院・医学研究院, 助教 (00322636)
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| Co-Investigator(Renkei-kenkyūsha) |
SHOZU Makio 千葉大学, 大学院・医学研究院, 教授 (30226302)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 婦人科腫瘍学 / 卵巣がん / がん幹細胞 / 化学療法 |
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| Research Abstract |
The objective of the current study is to clarify the association between positive metastatic lymph node and peritoneal cytology status and CA125 status at interval debulking surgery so that we could predict lymph node status before interval debulking surgery. Among patients, we performed retroperitoneal lymphadenectomy for 19 patients. 6 patients had positive lymph node status. In analysis for CA125, patients with yN1 had significantly longer period required until CA125 decreasing under 35 IU/ml than patients with yN0 ( yN1 ; 35.6 weeks, yN0 ; 7.1 weeks). The median period until peritoneal cytology revealed negative was 19.1 weeks. In analysis for peritoneal cytology, patients with yN1 had significantly longer period required until negative cytology status than patients with yN0 ( yN1 ; 37.4 weeks, yN0 ; 20.3 weeks). The longer period for CA125 value decreasing under 35IU/ml and peritoneal cytology revealed for negative could predict positive lymph node status.
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