Regeneration study of olfactory bulb neurons using bone marrow stem cells
Project/Area Number |
20791196
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Otorhinolaryngology
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Research Institution | Okayama University |
Principal Investigator |
YOSHINOBU Junko Okayama University, 医学部, 技術専門職員 (80448224)
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Project Period (FY) |
2008 – 2009
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Project Status |
Completed (Fiscal Year 2009)
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Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Keywords | 再生医学 / 細胞・組織 / 脳・神経 |
Research Abstract |
The regenerative therapy using bone marrow stem cells progressing remarkably in late years is expected as a new therapy for severe olfaction disorder that recovery is difficult by the current medical care. This study was conducted to examine the efficacy of the regenerative therapy using bone marrow cells in regeneration of olfactory bulb said to be more difficult than olfactory epithelium. As a result, it was found that the regenerative therapy using bone marrow cells had potential as a new therapy for not only the disorder of olfactory epithelium but also the disorder of olfactory bulb. Also, it was suggested that the use of cytokine raised efficacy of the regenerative therapy more.
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Report
(3 results)
Research Products
(4 results)
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[Journal Article] Sequential expressions of Notch1, Jagged2 and Math1 in molar tooth germ of mouse2008
Author(s)
Borkosky SS, Nagatsuka H, Orita Y, Tsujigiwa H, Yoshinobu J, Gunduz M, Rodriguez AP, Missana LR, Nishizaki K, Nagai N
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Journal Title
Biocell 32(3)
Pages: 251-8
Related Report
Peer Reviewed
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