Project/Area Number |
20791515
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Surgical dentistry
|
Research Institution | Okayama University |
Principal Investigator |
TSUJIGIWA Hidetsugu Okayama University, 大学院・医歯薬学総合研究科, 助教 (70335628)
|
Research Collaborator |
NAGATUSKA Hitoshi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (70237535)
YAMADA Masao 岡山大学, 大学院・医歯薬学総合研究科, 教授 (40166731)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 再生医学 / 骨髄幹細胞 / 歯 / GFP / 分化 / 肝細胞 / 歯髄細胞 / 骨髄細胞 / 再生医療 / 細胞分化 / 幹細胞 / 歯髄 / 骨髄 |
Research Abstract |
This research was performed as a fundamental study for the clinical application of tooth regenerative medicine. In this research, we explored the possibility of guided differentiation induction of tooth component cells from bone marrow stem cells. The results revealed that bone marrow stem cells might possess differentiation capacity into tooth component cells and periodontal ligament. Moreover, stem cells in the dental pulp might bear similar characteristics with bone marrow stem cells. All the results demonstrated that the possible utilization of bone marrow stem cells in the prospective tooth regeneration medicine.
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