Clarification of pain mechanism and pain control during orthodontic treatment
Project/Area Number |
20791574
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Orthodontic/Pediatric dentistry
|
Research Institution | Okayama University |
Principal Investigator |
YABUUCHI Toshinori Okayama University, 岡山大学病院, 医員 (00452582)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 神経ペプチド / 痛み / 共焦点顕微鏡 / 組織学的形態計測 |
Research Abstract |
We found that the distribution of various markers in central have been changed over time during tooth movement. In trigeminal ganglion, we found that microglia and astrocytes were activated during tooth movement. In addition, activated glial cells were localized around the Fos-positive neurons. The results of studies were suggested glial cells may have been deeply involved in noxious stimulation during tooth movement.
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Report
(3 results)
Research Products
(3 results)