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Newly Caries Prevention System by CPP-ACP-induced Remineralized dentin

Research Project

Project/Area Number 20791594
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthodontic/Pediatric dentistry
Research InstitutionThe Nippon Dental University

Principal Investigator

WARITA Sachie  The Nippon Dental University, 生命歯学部, 講師 (50386257)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
KeywordsCPP-ACP / 象牙質 / 再石灰化 / 脱灰抑制 / 齲蝕
Research Abstract

This study suggested that the validity of the using μCT to evaluate the effect of Casein phosphopeptide-amorphous calcium phosphate(CPP-ACP) on demineralized bovine dentin. However it was difficult to measure the initial remineralization on the dentin in this experimental condition. And for preparing clinical study, the non-invasive evaluation on human extracted deciduous teeth using quantitative light-induced fluorescence (QLF) was done. It was found the possibility to measure the effects of remineralization on deciduous teeth easily. It was suggested that the human deciduous teeth which recently extracted were not so suitable for de/reminelalizaion studies.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (5 results)

All 2010 2009 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Combined Effect of Paste Containing CPP-ACP and Fluoride on Enamel Lesions: An in vitro pH-cycling Study2010

    • Author(s)
      Kiyokazu Ogata, Sachie Warita, Kisaki Shimazu, Tomomi Kawakami, Kyoko Aoyagi, Hiroyuki Karibe
    • Journal Title

      Pediatric Dentistry 32巻(投稿中)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Combined Effect of Paste Containing CPP-ACP and Fluoride on Enamel Lesions : An in vitro pH-cycling Study2010

    • Author(s)
      Kiyokazu Ogata
    • Journal Title

      Pediatric Dentistry 32

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Micro-computed tomographic evaluation of effects of CPP-ACP on demineralized dentin2009

    • Author(s)
      割田幸恵
    • Organizer
      第22回国際小児歯科学会
    • Place of Presentation
      ドイツ・ミュンヘン
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] The effects of CPP-ACP with fluoride on demineralised dentine2008

    • Author(s)
      割田幸恵
    • Organizer
      第19回国際障害者歯科学会
    • Place of Presentation
      ブラジル・サントス
    • Related Report
      2009 Final Research Report
  • [Presentation] Theeffbcts of CPP-ACP with fluoride on demineralised dentine2008

    • Author(s)
      割田幸恵
    • Organizer
      第19回国際障害者歯科学会
    • Place of Presentation
      ブラジル・サントス
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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