The expression of bone resorption factors in gingival tissue of the experimental periodontitis using the diabetic model rats.

• Project/Area Number: 20791629
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Periodontal dentistry
• Research Institution: Aichi Gakuin University
• Principal Investigator: KIKUCHI Takeshi Aichi Gakuin University, 歯学部, 講師 (40421242)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 歯周免疫機能学 / 糖尿病 / 歯周病 / Periodontal Medicine / LBP / 骨吸収

Research Abstract

The results of the present study indicate that the role of diabetes in modulating bone destruction in periodontal disease may involve increased level of LBP and reduced levels of Th2 cytokines. A better understanding of infectious bone resorption in diabetes and the immune response could explain the relationship between periodontitis and diabetes.

Research Products

• [Presentation] Study of gene expression in gingival tissue of the experimental periodontitis using the diabetic model rats. (2009)
  • Author(s): T. Noguchi, K. Soboku, S. Fujita, T. Kikuchi
  • Organizer: The 95th annual meeting of the American Academy of Periodontology
  • Place of Presentation: Boston, USA
  • Year and Date: 2009-09-14
• [Presentation] Study of gene expression in gingival tissue of the experimental periodontitis using the diabetic model rats (2009)
  • Author(s): T.Noguchi, T.Kikuchi etc.
  • Organizer: The 95^<th> annual meeting of the American Academy of Periodontology
  • Place of Presentation: Boston, USA
  • Year and Date: 2009-09-14
• [Presentation] Study of gene expression in gingival tissue of the experimental periodontitis using the diabetic model rats. (2009)
  • Author(s): T. Noguchi, K. Soboku, S. Fujita, T. Kikuchi
  • Organizer: Europerio6
  • Place of Presentation: Stockholm, Sweden
  • Year and Date: 2009-06-05
• [Presentation] 糖尿病疾患モデルラットにおける歯周組織の遺伝子発現の検討 (2008)
  • Author(s): 惣卜響子, 菊池毅, 木下幸子, 野口英俊
  • Organizer: 第51回日本歯周病学会秋期学術大会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-10-19
• [Presentation] 糖尿病疾患モデルラットを用いた歯周組織における遺伝子発現の検討 (2008)
  • Author(s): 惣卜響子(代表)
  • Organizer: 第51回秋期日本歯周病学会
  • Place of Presentation: 四日市
  • Year and Date: 2008-10-19
• [Presentation] 糖尿病疾患モデルラットにおける歯周組織の遺伝子発現の検討 (2008)
  • Author(s): 惣卜響子, 菊池毅, 木下幸子, 野口英俊
  • Organizer: 第72回愛院大歯学会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-06-01