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Neural mechanisms underlying memory distortion as revealed by functional neuroimaging

Research Project

Project/Area Number 20800006
Research Category

Grant-in-Aid for Young Scientists (Start-up)

Allocation TypeSingle-year Grants
Research Field Cognitive science
Research InstitutionTohoku University

Principal Investigator

ABE Nobuhito  Tohoku University, 大学院・医学系研究科, 助教 (90507922)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥2,821,000 (Direct Cost: ¥2,170,000、Indirect Cost: ¥651,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,781,000 (Direct Cost: ¥1,370,000、Indirect Cost: ¥411,000)
Keywords脳認知科学 / 記憶錯誤 / 虚再認 / 脳機能画像法 / 認知神経科学 / PET / fMRI / 内側側頭葉 / 前頭前野
Research Abstract

In the present study, I used functional magnetic resonance imaging to investigate the neural correlates of false recognition and deception in healthy individuals. I reported that the increased prefrontal activity was found in deception relative to false recognition and that the increased medial temporal-lobe (right anterior hippocampal) activity was found in false recognition relative to deception. As for the neural correlates of deception, I conducted a neuropsychological study of patients with Parkinson's disease and reported that the prefrontal cortex plays an important role in deception. I also published a review article on these findings.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (25 results)

All 2010 2009 2008

All Journal Article (17 results) (of which Peer Reviewed: 17 results) Presentation (6 results) Book (2 results)

  • [Journal Article] Neural correlates of forgiveness for moral transgressions involving deception2010

    • Author(s)
      Hayashi A, Abe N, Ueno A, Shigemune Y, Mori E, Tashiro M, Fujii T
    • Journal Title

      Brain Research 1332

      Pages: 90-99

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hippocampal activation associated with successful external source monitoring2010

    • Author(s)
      Mugikura S, Abe N, Suzuki M, Ueno A, Higano S, Takahashi S, Fujii T
    • Journal Title

      Neuropsychologia 48(6)

      Pages: 1543-1550

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of emotion and reward motivation on neural correlates of episodic memory encoding : a PET study2010

    • Author(s)
      Shigemune Y, Abe N, Suzuki M, Ueno A, Mori E, Tashiro M, Itoh M, Fujii T
    • Journal Title

      Neuroscience Research 67(1)

      Pages: 72-79

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Memory repression : Brain mechanisms underlying dissociative amnesia2010

    • Author(s)
      Kikuchi H, Fujii T, Abe N, Suzuki M, Takagi M, Mugikura S, Takahashi S, Mori E
    • Journal Title

      Journal of Cognitive Neuroscience 22(3)

      Pages: 602-613

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Memory repression : Brain mechanisms underlying dissociative amnesia2010

    • Author(s)
      Kikuchi, et al.
    • Journal Title

      Journal of Cognitive Neuroscience 22

      Pages: 602-613

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of emotion and reward motivation on neural correlates of episodic memory encoding : a PET study2010

    • Author(s)
      Shigemune, et al.
    • Journal Title

      Neuroscience Research (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hippocampal activation associated with successful external source monitoring2010

    • Author(s)
      Mugikura, et al.
    • Journal Title

      Neuropsychologia (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural correlates of forgiveness for moral transgressionsinvolving deception2010

    • Author(s)
      Hayashi, et al.
    • Journal Title

      Brain Research (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The neurobiology of deception : evidence from neuroimaging and loss-of-function studies2009

    • Author(s)
      Abe N
    • Journal Title

      Current Opinion in Neurology 22

      Pages: 594-600

    • Related Report
      2009 Annual Research Report 2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reactivation of medial temporal lobe and human V5/MT+ during the retrieval of motion information : a PET study2009

    • Author(s)
      Ueno A, Abe N, Suzuki M, Shigemune Y, Hirayama K, Mori E, Tashiro M, Itoh M, Fujii T
    • Journal Title

      Brain Research 1285

      Pages: 127-134

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Do parkinsonian patients have trouble telling lies? The neurobiological basis of deceptive behaviour2009

    • Author(s)
      Abe N, Fujii T, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Nishio Y, Suzuki K, Itoyama Y, Takahashi S, Fukuda H, Mori E
    • Journal Title

      Brain 132(5)

      Pages: 1386-1395

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Do parkinsonian patients have trouble telling lies? The neurobiological basis of deceptive behaviour2009

    • Author(s)
      Abe, et al.
    • Journal Title

      Brain 132

      Pages: 1386-1395

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reactivation of medial temporal lobe and human V5/MT+ during the retrieval of motion information : a PET study2009

    • Author(s)
      Ueno, et al.
    • Journal Title

      Brain Research 1285

      Pages: 127-134

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural correlates of true memory, false memory, and deception2008

    • Author(s)
      Abe N, Okuda J, Suzuki M, Sasaki H, Matsuda T, Mori E, Tsukada M, Fujii T
    • Journal Title

      Cerebral Cortex 18(12)

      Pages: 2811-2819

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneously cooperative, but serially antagonistic : A neuropsychological study of diagonistic dyspraxia in a case of Marchiafava-Bignami disease2008

    • Author(s)
      Hirayama K, Tachibana K, Abe N, Manabe H, Fuse T, Tsukamoto T
    • Journal Title

      Behavioural Neurology 19(3)

      Pages: 137-144

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural correlates of true memory, false memory, and deception2008

    • Author(s)
      Abe, et.al.
    • Journal Title

      Cerebral Cortex 18(12)

      Pages: 2811-2819

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneously cooperative, but serially antagonistic : A neuropsychological study of diagonistic dyspraxia in a case of Marchiafava-Bignami disease2008

    • Author(s)
      Hirayama, et.al.
    • Journal Title

      Behavioural Neurology 19(3)

      Pages: 137-144

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 正直なPD-嘘をつかないのか、つけないのか2009

    • Author(s)
      阿部修士
    • Organizer
      第14回日本神経精神医学会
    • Place of Presentation
      仙台
    • Year and Date
      2009-11-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] The role of prefrontal cortex in deception : evidence from functional neuroimaging2009

    • Author(s)
      Abe N
    • Organizer
      The 8th Biennial Meeting of the Society for Applied Research in Memory and Cognition
    • Place of Presentation
      京都
    • Year and Date
      2009-07-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Right temporal lobe activity associated with the retrieval of family relationships in person identification : A positron emission tomography study2009

    • Author(s)
      Abe, et al.
    • Organizer
      15th Annual meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      San Francisco, U.S.A
    • Year and Date
      2009-06-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] Right temporal lobe activity associated with the retrieval of family relationships in person identification : A positron emission tomography study2009

    • Author(s)
      Abe N, Ueno A, Shigemune Y, Suzuki M, Mori E, Tashiro M, Fujii T.
    • Organizer
      15th Annual meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2009 Final Research Report
  • [Presentation] 正直なPD-嘘をつかないのか、つけないのか2009

    • Author(s)
      阿部修士
    • Organizer
      第14回日本神経精神医学会
    • Place of Presentation
      仙台(口頭発表)
    • Related Report
      2009 Final Research Report
  • [Presentation] The role of prefrontal cortex in deception : evidence from functional neuroimaging2009

    • Author(s)
      Abe N
    • Organizer
      The 8th Biennial Meeting of the Society for Applied Research in Memory and Cognition (SARMAC)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2009 Final Research Report
  • [Book] 第VIII部 脳血管障害と神経心理学VIII-12. 記憶障害 脳卒中症候学(田川皓一編)2010

    • Author(s)
      藤井俊勝, 阿部修士, 森悦朗
    • Publisher
      西村書店 東京
    • Related Report
      2009 Final Research Report
  • [Book] 脳卒中症候学(第VIII部 脳血管障害と神経心理学. VIII-12. 記憶障害)2010

    • Author(s)
      藤井俊勝, 阿部修士, 森悦朗
    • Total Pages
      13
    • Publisher
      西村書店
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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