Cloning and Expression of Marine Natural Product Biosynthetic by Function Based Screening
Project/Area Number |
20810022
|
Research Category |
Grant-in-Aid for Young Scientists (Start-up)
|
Allocation Type | Single-year Grants |
Research Field |
Living organism molecular science
|
Research Institution | Kumamoto University |
Principal Investigator |
FUJITA Masaki Kumamoto University, 大学院・先導機構, 特定事業教員 (30505251)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
|
Keywords | 海洋天然物 / 生合成 / メタゲノム / 生合成遺伝子 / 生理活性物質 / 異宿主生産 / 色素生合成 / 薬剤耐性 / 生物有機化学 |
Research Abstract |
Metagenomics is a promising method to obtain useful genes from environmental samples. In order to prove that metagenomics is applicable to produce marine natural products, high quality marine metagenomic library consist of about 100 thousands clones was constructed. More than 300 pigment producing clones were screened from the library and their biosynthetic genes and products were characterized.
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Report
(3 results)
Research Products
(19 results)