| Project/Area Number |
20890200
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
|---|
| Research Field |
Anesthesiology/Resuscitation studies
|
|---|
| Research Institution | Wakayama Medical University |
|---|
Principal Investigator |
KOBAYASHI Yuka Wakayama Medical University, 医学部, 助教 (20511562)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥2,626,000 (Direct Cost: ¥2,020,000、Indirect Cost: ¥606,000)
Fiscal Year 2009: ¥1,404,000 (Direct Cost: ¥1,080,000、Indirect Cost: ¥324,000)
Fiscal Year 2008: ¥1,222,000 (Direct Cost: ¥940,000、Indirect Cost: ¥282,000)
|
|---|
| Keywords | 神経障害性疼痛 / スフィンゴ脂質 / グリア細胞 / サイトカイン / アロディニア / セラミド / 中枢神経 / アロデイニア / 痛覚過敏 / ミクログリア / 脂質 |
|---|
| Research Abstract |
In this study, the involvement of spinal ceramide in neuropathic pain through microglia activation and inflammatory cytokines increase was revealed. Therefore, ceramide was nominated as a novel therapeutic target of neuropathic pain.
|
