Distinct regulatory functions of SLP-76 is required for the high affinity IgE receptor- and cytokine receptors-induced activation of basophils.

• Project/Area Number: 20890232
• Research Category: Grant-in-Aid for Young Scientists (Start-up)
• Allocation Type: Single-year Grants
• Research Field: Immunology
• Research Institution: Tokyo University of Science
• Principal Investigator: HIDANO Shinya Tokyo University of Science, 生命科学研究所, 助教 (80516386)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
• Keywords: 免疫学 / アレルギー・ぜんそく / シグナル伝達

Research Abstract

Whether functions of SLP-76 is required for the high affinity IgE receptor- and cytokine receptors-induced activation of basophils in allergy inflammation, we showed that SLP-76 regulates these receptor-mediate downstream signal pathways by distinct mechanism.

Research Products

• [Presentation] SLP-76 is regulated for the high affinity IgE receptor and cytokine receptors-induced activation of basophils. (2008)
  • Author(s): 飛弾野 真也
  • Organizer: 第38回日本免疫学会総会・学術集会
  • Place of Presentation: 京都府・国立京都国際会館
  • Year and Date: 2008-12-03
• [Presentation] Distinct regulatory functions of SLP-76 is required for the high affinity IgE receptor- and cytokine receptors-induced activation of basophils. (2008)
  • Author(s): HIDANO Shinya, ARIKI Reina, KITAMURA Daisuke, GOITSUKA Ryo
  • Organizer: 第38回日本免疫学会総会・学術集会
  • Place of Presentation: 京都