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Construction of diagnostic probability system indicate cervical lymph node metastasis using MRI

Research Project

Project/Area Number 20890275
Research Category

Grant-in-Aid for Young Scientists (Start-up)

Allocation TypeSingle-year Grants
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionFukuoka Dental College

Principal Investigator

FUKUNARI Fumiko  Fukuoka Dental College, 歯学部, 医員 (30510234)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥3,224,000 (Direct Cost: ¥2,480,000、Indirect Cost: ¥744,000)
Fiscal Year 2009: ¥1,534,000 (Direct Cost: ¥1,180,000、Indirect Cost: ¥354,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords頸部リンパ節 / 口腔癌 / リンパ節転移 / MRI / 歯学 / 癌
Research Abstract

1. MR images obtained before surgery were correlated with the histopathological architecture of the cervical lymph nodes from oral squamous cell carcinoma obtained by neck dissection. On T2-weighted images, Very hyperintese and isointense areas were specific findings for lymph nodes containing metastases. On diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) images, it was difficult to differentiate metastatic from benign lymph nodes. 2. The positive predictive value (PPV) of each MRI findings, such as the signal intensity of the lymph node parenchyma on T2-weighted images, the pattern of signal intensity curve in dynamic MRI, were calculated. Using the PPV defined as diagnostic probability, the diagnostic results of cervical lymph node metastasis from oral squamous cell carcinoma using MRI may be quantitated.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (3 results)

All 2008 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results)

  • [Journal Article] Cervical lymph nodes with or without metastases from oral squamous carcima: A correlation of MRI findings and histopathologic architecture

    • Author(s)
      Fumiko Fukunari, Kazuhiko Okamura, Ryousuke Zeze, Toyohiro Kagawa, Kenichiro Hashimoto, Kenji Yuasa.
    • Journal Title

      Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology (in press)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cervical lymph nodes with or without metastases from oral squamous carcima : A correlation of MRI findings and histopathologic architecture

    • Author(s)
      Fumiko Fukunari, et al.
    • Journal Title

      Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology (in press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] MR imaging characteristics of cervical metastatic lymph nodes2008

    • Author(s)
      Fumiko Fukunari, Kazuhiko Okamura, R Zeze, Ryousuke Zeze, Toyohiro Kagawa, Kenji Yuasa
    • Organizer
      第7回アジア口腔顎顔面放射線学会議
    • Place of Presentation
      奈良
    • Year and Date
      2008-11-22
    • Related Report
      2009 Final Research Report 2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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