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Identification of trace molecules with graphene devices based on static and dynamic analysis

Research Project

Project/Area Number 20H02159
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 21030:Measurement engineering-related
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

Takashi Ikuta  東京農工大学, 工学(系)研究科(研究院), 助教 (80805929)

Co-Investigator(Kenkyū-buntansha) 正井 宏  東京大学, 大学院総合文化研究科, 助教 (70793149)
玉木 孝  京都大学, 工学研究科, 研究員 (90815490)
Project Period (FY) 2020-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2022: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2021: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2020: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Keywordsグラフェン / 分子検出 / センサ / 微量検出 / 検出素子 / 超分子
Outline of Research at the Start

本研究では、小型微量化学種分析装置の開発に必要となる高感度な官能基及び分子骨格の識別が可能な電子素子の開発及び、電子素子の静・動的な評価手法用いた分子検出機構の確立を行う。本研究では、目標の実現に向け、超分子修飾グラフェンを用いた官能基識別素子の開発を目指す。これはグラフェンデバイスに超分子化学の化学的相補性という観点を加えることで、微量有機化学種の官能基・骨格に由来する静的・動的な変化をデバイスパラメータの変化として信号抽出を可能にし、分子構造を判別するシステムの基幹技術となりうる素子を実現する。

Outline of Final Research Achievements

In this study, by modifying a supramolecule on graphene and then introducing a small amount of the target molecule at the parts-per-billion level, we have successfully observed changes in static transfer characteristics and frequency domain on a graphene field-effect transistor. This has opened up the possibility of molecular detection using frequency domain, which has not been used in the past, as well as the application to the evaluation of the electronic state of molecules by adsorption of the target molecules.

Academic Significance and Societal Importance of the Research Achievements

本研究では、従来から利用されてきたグラフェン電界効果トランジスタの静的な伝達特性評価と、動的な周波数特性を利用することで新たな分子検出手法の開拓を行った。これは、グラフェンデバイスの新たな応用分野を提案するとともに、従来の分子センサでは実現が困難であった分子の電子状態を評価が可能である。これらのことから、グラフェンの応用分野開拓のみならず、分子評価の新規手法の確立という、学術・応用のそれぞれの領域に広く貢献できる研究成果となっている。

Report

(3 results)
  • 2022 Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • Research Products

    (7 results)

All 2022 2021

All Journal Article (6 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results,  Open Access: 4 results) Presentation (1 results)

  • [Journal Article] Effect of changing electronic states of molecules on frequency domain of graphene FETs2022

    • Author(s)
      Oketa Tomohiro、Ikuta Takashi、Masai Hiroshi、Tamaki Takashi、Terao Jun、Maehashi Kenzo
    • Journal Title

      Applied Physics Express

      Volume: 15 Issue: 4 Pages: 045001-045001

    • DOI

      10.35848/1882-0786/ac564d

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Stochastic Binding Dynamics of a Photoswitchable Single Supramolecular Complex2022

    • Author(s)
      Su Dingkai、Zhou Shuyao、Masai Hiroshi、Liu Zihao、Zhou Ce、Yang Chen、Li Zhizhou、Tsuda Susumu、Liu Zhirong、Terao Jun、Guo Xuefeng
    • Journal Title

      Advanced Science

      Volume: 9 Issue: 13 Pages: 2200022-2200022

    • DOI

      10.1002/advs.202200022

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Precision synthesis of linear oligorotaxanes and polyrotaxanes achieving well-defined positions and numbers of cyclic components on the axle2022

    • Author(s)
      Masai Hiroshi、Oka Yuki、Terao Jun
    • Journal Title

      Chemical Communications

      Volume: 58 Issue: 11 Pages: 1644-1660

    • DOI

      10.1039/d1cc03507j

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of an odorant sensor with a cell-free synthesized olfactory receptor and a graphene field-effect transistor2022

    • Author(s)
      Yoshii Tomoya、Takayama Ikumi、Fukutani Yosuke、Ikuta Takashi、Maehashi Kenzo、Yohda Masafumi
    • Journal Title

      Analytical Sciences

      Volume: 38 Issue: 2 Pages: 241-245

    • DOI

      10.1007/s44211-022-00073-y

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Electrical detection of ppb region NO<sub>2</sub> using Mg-porphyrin-modified graphene field-effect transistors2021

    • Author(s)
      Ikuta Takashi、Tamaki Takashi、Masai Hiroshi、Nakanishi Ryudai、Endo Kitaro、Terao Jun、Maehashi Kenzo
    • Journal Title

      Nanoscale Advances

      Volume: 3 Issue: 20 Pages: 5793-5800

    • DOI

      10.1039/d1na00519g

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Electrical Detection of Molecular Transformations Associated with Chemical Reactions Using Graphene Devices2021

    • Author(s)
      Yuri Sakamoto, Takashi Ikuta, and Kenzo Maehashi
    • Journal Title

      ACS Applied Materials & Interfaces

      Volume: 13-37 Issue: 37 Pages: 45001-45007

    • DOI

      10.1021/acsami.1c09985

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Presentation] Mnフタロシアニン修飾GFETのガス応答性2021

    • Author(s)
      中西竜大、生田昂、前橋兼三
    • Organizer
      第68回応用物理学会春季学術講演会
    • Related Report
      2020 Annual Research Report

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Published: 2020-04-28   Modified: 2024-12-25  

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