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Fabrication of magnesium/calcium phosphate lamellar composite

Research Project

Project/Area Number 20K05132
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 26040:Structural materials and functional materials-related
Research InstitutionKobe University

Principal Investigator

IKEO Naoko  神戸大学, 工学研究科, 准教授 (80647644)

Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2022: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2021: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2020: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords生体内分解性材料 / 生体内分解性コンポジット / 複合材料 / 生体内分解性マグネシウム / 熱間加工
Outline of Research at the Start

マグネシウムの表面にリン酸カルシウムを被覆後、熱間圧接により層状複合構造体を作製する。複合材の機械的性質に対するリン酸カルシウム層の厚み、体積率等の構造パラメータによる機械的性質および生体内分解性への影響の解明を試みる。また、リン酸カルシウム層形成後の熱間接合プロセスによる微細組織制御の可能性を検討する。

Outline of Final Research Achievements

I succeeded in development of magnesium/calcium phosphate laminated composite. Furthermore, it was shown that the volume fraction and position of calcium phosphate can be arbitrarily controlled by optimizing the processing conditions.
It was confirmed that the yield strength and degradation resistance of the composite increased linearly with the volume fraction of calcium phosphate. It can be said that magnesium/calcium phosphate composites with the intended properties can be fabricated by controlling the volume fraction of calcium phosphate.

Academic Significance and Societal Importance of the Research Achievements

整形外科領域において、生体内分解性デバイスの需要は高い。また、生体骨組織は体を支持するために、異方的な構造を示すため、骨組織の異方性に合わせたデバイスの開発がQOLの向上に有効であることが明らかとなっている。本研究により、骨類似の異方性を示し、骨との親和性の高い生体内分解性材料が開発できた。本材料を用いたデバイスの開発は、使用者のQOL向上につながると考えられる。

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (3 results)

All 2022 2021

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (2 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Effect of Grain Refinement on Fatigue Properties of Mg–0.3 at%Ca Alloy in Air and Simulated Body Fluid2022

    • Author(s)
      Naoko Ikeo, Naoya Kawamura, Toshiji Mukai
    • Journal Title

      MATERIALS TRANSACTIONS

      Volume: 63 Issue: 1 Pages: 69-72

    • DOI

      10.2320/matertrans.MT-M2021186

    • NAID

      130008134286

    • ISSN
      1345-9678, 1347-5320
    • Year and Date
      2022-01-01
    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Evaluation of mechanical properties and bio-degradability in magnesium/calcium phosphate lamellar composite2021

    • Author(s)
      NAOKO IKEO, Yuka Yamashita, Kana NAKANO, Toshiji MUKAI
    • Organizer
      MRM2021
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] 生体内分解性マグネシウム/β-TCP積層複合構造体の創製2021

    • Author(s)
      池尾直子、山下優香、向井敏司
    • Organizer
      日本金属学会春期(第168回)講演大会
    • Related Report
      2020 Research-status Report

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Published: 2020-04-28   Modified: 2025-01-30  

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