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Development of pseudo bone implant by additive manufacturing using mixture powders

Research Project

Project/Area Number 20K05141
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 26040:Structural materials and functional materials-related
Research InstitutionNiihama National College of Technology

Principal Investigator

Todai Mitsuharu  新居浜工業高等専門学校, 環境材料工学科, 准教授 (10610800)

Co-Investigator(Kenkyū-buntansha) 真中 俊明  新居浜工業高等専門学校, 環境材料工学科, 准教授 (60805068)
Project Period (FY) 2020-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2022: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2021: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2020: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords金属3Dプリンタ / レーザ積層造形法 / 生体材料 / チタン合金 / 金属積層造形 / 金属3Dプリンタ / レーザ積層造形 / 微細組織 / 集合組織 / 金属積層造形法 / 生体用インプラント
Outline of Research at the Start

我々の研究グループでは独自の骨代替インプラント用β-Ti合金の設計指針を構築し、これに基づいて[001]方位において生体骨程度の低ヤング率を有するインプラントの開発を提案している。本研究では成分元素の混合粉比率によって所望の組成(e/a)を選択し、さらに金属積層造形法により熱流方位を制御することで[001]方位に結晶の集合組織を発現させる。このことにより、患者一人一人に合い、かつ低ヤング率を示すカスタムメイドインプラントを開発する。

Outline of Final Research Achievements

The fabrication the Ti-Cr alloys from a mixture of pure elemental powders was achieved using selective laser melting process(SLM). The Ti-Cr alloys comprise β-Ti single-phase without any non-molten particles and macroscopic defects. The crystallographic texture of these βphase in Ti-Cr alloys can be controlled effectively by optimizing the process parameters. The growth of {001}〈100〉crystallographic orientation during the SLM process is discussed based on the solidification process focusing on the columnar cell growth in the melt pool. These results imply the possibility of fabricating the Ti-based alloys with well-developed crystallographic texture from the mixture of pure elemental powders using the process of SLM. These results will greatly contribute to the future development of the additive manufacturing process.

Academic Significance and Societal Importance of the Research Achievements

本研究の目的遂行は、ターゲットとしているβ-Ti合金のみならず、様々な合金系へと波及することが予想され、例えば造形機に粉末混合機を搭載させることで、ボタン1つで自在に合金系・組成・形状・組織を制御し、製品を作ることのできるプロセスの構築につながると考えられる。このことは言うまでもなく、今後の積層造形法を用いた製造プロセスの一層の普及に直結し、金属3Dプリンタを用いた製造技術発展とこれに関する市場拡大に大きく寄与するといえる。

Report

(4 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (41 results)

All 2023 2022 2021 2020 Other

All Journal Article (15 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 15 results,  Open Access: 11 results) Presentation (17 results) (of which Int'l Joint Research: 3 results) Book (3 results) Remarks (6 results)

  • [Journal Article] Influence of Input Energy Density on Morphology of Unique Layered Microstructure of γ-TiAl Alloys Fabricated by Electron Beam Powder Bed Fusion2023

    • Author(s)
      Ken Cho, Naohide Morita, Hiromasa Matsuoka, Hiroyuki Y. Yasuda, Mitsuharu Todai, Minoru Ueda, Masao Takeyama, Takayoshi Nakano
    • Journal Title

      MATERIALS TRANSACTIONS

      Volume: 64 Issue: 1 Pages: 44-49

    • DOI

      10.2320/matertrans.MT-MLA2022015

    • ISSN
      1345-9678, 1347-5320
    • Year and Date
      2023-01-01
    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ternary Diffusion and Thermodynamic Interaction in the β Solid Solutions of Ti–Al–Zr Alloys at 1473 K2022

    • Author(s)
      Takahashi Tomoshi、Minamino Yoritoshi、Manaka Toshiaki、Todai Mitsuharu
    • Journal Title

      MATERIALS TRANSACTIONS

      Volume: 63 Issue: 12 Pages: 1597-1606

    • DOI

      10.2320/matertrans.MT-L2022018

    • NAID

      130008141701

    • ISSN
      1345-9678, 1347-5320
    • Year and Date
      2022-12-01
    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Influence of input energy density on morphology of unique layered microstructure of <i>γ</i>-TiAl alloys fabricated by electron beam powder bed fusion2022

    • Author(s)
      趙 研, 森田 尚秀, 松岡 弘剛, 安田 弘行, 當代 光陽, 上田 実, 竹山 雅夫, 中野 貴由
    • Journal Title

      Journal of Japan Institute of Light Metals

      Volume: 72 Issue: 6 Pages: 298-303

    • DOI

      10.2464/jilm.72.298

    • ISSN
      0451-5994, 1880-8018
    • Year and Date
      2022-06-15
    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Design and development of (Ti, Zr, Hf)-Al based medium entropy alloys and high entropy alloys2022

    • Author(s)
      Nagase Takeshi、Todai Mitsuharu、Wang Pan、Sun Shi-Hai、Nakano Takayoshi
    • Journal Title

      Materials Chemistry and Physics

      Volume: 276 Pages: 125409-125409

    • DOI

      10.1016/j.matchemphys.2021.125409

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] チタン含有生体用ハイエントロピー合金の研究・開発2022

    • Author(s)
      小笹良輔、松垣あいら、當代光陽、石本卓也、永瀬丈嗣、中野貴由
    • Journal Title

      チタン

      Volume: 68 Pages: 44-52

    • NAID

      40022821664

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Ternary diffusion and thermodynamic interaction in the <i>β</i> solid solutions of Ti-Al-Zr alloys at 1473 K2021

    • Author(s)
      Takahashi Tomoshi、Minamino Yoritoshi、Manaka Toshiaki、Todai Mitsuharu
    • Journal Title

      Journal of Japan Institute of Light Metals

      Volume: 71 Issue: 12 Pages: 539-548

    • DOI

      10.2464/jilm.71.539

    • NAID

      130008141701

    • ISSN
      0451-5994, 1880-8018
    • Year and Date
      2021-12-15
    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Development of TiNbTaZrMo bio-high entropy alloy (BioHEA) super-solid solution by selective laser melting, and its improved mechanical property and biocompatibility2021

    • Author(s)
      Ishimoto Takuya、Ozasa Ryosuke、Nakano Kana、Weinmann Markus、Schnitter Christoph、Stenzel Melanie、Matsugaki Aira、Nagase Takeshi、Matsuzaka Tadaaki、Todai Mitsuharu、Kim Hyoung Seop、Nakano Takayoshi
    • Journal Title

      Scripta Materialia

      Volume: 194 Pages: 113658-113658

    • DOI

      10.1016/j.scriptamat.2020.113658

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Fabrication of Be-Ta Ti Alloys without Pre-Alloyed Powders via SLM2021

    • Author(s)
      Todai Mitsuharu、Nagase Takeshi、Nakano Takayoshi
    • Journal Title

      Materials Science Forum

      Volume: 1016 Pages: 1797-1801

    • DOI

      10.4028/www.scientific.net/msf.1016.1797

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Improvement of High Temperature Fatigue Properties of TiAl Alloys Fabricated by Electron Beam Melting Through Hot Isostatic Pressing Process2020

    • Author(s)
      CHO Ken、YASUDA Hiroyuki、TODAI Mitsuharu、UEDA Minoru、TAKEYAMA Masao、NAKANO Takayoshi
    • Journal Title

      Journal of Smart Processing

      Volume: 9 Issue: 4 Pages: 180-184

    • DOI

      10.7791/jspmee.9.180

    • NAID

      130007877778

    • ISSN
      2186-702X, 2187-1337
    • Year and Date
      2020-07-10
    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Development of Co–Cr–Mo–Fe–Mn–W and Co–Cr–Mo–Fe–Mn–W–Ag High-Entropy Alloys Based on Co–Cr–Mo Alloys2020

    • Author(s)
      Nagase Takeshi、Todai Mitsuharu、Nakano Takayoshi
    • Journal Title

      MATERIALS TRANSACTIONS

      Volume: 61 Issue: 4 Pages: 567-576

    • DOI

      10.2320/matertrans.MT-MK2019002

    • NAID

      130007815389

    • ISSN
      1345-9678, 1347-5320
    • Year and Date
      2020-04-01
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Behavior of hydrogen in a low carbon high strength steel2020

    • Author(s)
      Manaka Toshiaki、Todai Mitsuharu、Hino Takanori
    • Journal Title

      Transactions of the Materials Research Society of Japan

      Volume: 45 Issue: 1 Pages: 5-7

    • DOI

      10.14723/tmrsj.45.5

    • NAID

      130007793991

    • ISSN
      1382-3469, 2188-1650
    • Year and Date
      2020-02-01
    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Development and Perspectives of High Entropy alloys composed by light metal elements and that for metallic biomaterials with BCC2020

    • Author(s)
      當代 光陽、永瀬 丈嗣、中野 貴由
    • Journal Title

      Journal of Japan Institute of Light Metals

      Volume: 70 Issue: 1 Pages: 14-23

    • DOI

      10.2464/jilm.70.14

    • NAID

      130007837642

    • ISSN
      0451-5994, 1880-8018
    • Year and Date
      2020-01-25
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Kinetic Arrest of R-B19′ Transformation in Iron-Doped Ti–Ni Shape Memory Alloy2020

    • Author(s)
      Todai Mitsuharu、Fukuda Takashi、Kakeshita Tomoyuki
    • Journal Title

      MATERIALS TRANSACTIONS

      Volume: 61 Issue: 1 Pages: 49-54

    • DOI

      10.2320/matertrans.MT-MJ2019006

    • NAID

      130007772509

    • ISSN
      1345-9678, 1347-5320
    • Year and Date
      2020-01-01
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of Ti-Zr-Hf-Y-La high-entropy alloys with dual hexagonal-close-packed structure2020

    • Author(s)
      Nagase Takeshi、Todai Mitsuharu、Nakano Takayoshi
    • Journal Title

      Scripta Materialia

      Volume: 186 Pages: 242-246

    • DOI

      10.1016/j.scriptamat.2020.05.033

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Liquid Phase Separation in Ag-Co-Cr-Fe-Mn-Ni, Co Cr-Cu-Fe-Mn-Ni and Co-Cr-Cu-Fe-Mn-Ni-B High Entropy Alloys for Biomedical Application2020

    • Author(s)
      Nagase Takeshi、Todai Mitsuharu、Nakano Takayoshi
    • Journal Title

      Crystals

      Volume: 10 Issue: 6 Pages: 527-527

    • DOI

      10.3390/cryst10060527

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] スタート材として合金粉末を使用しないレーザ積層造形法によるTi-Nb超伝導材料の開発2022

    • Author(s)
      高橋直哉, 當代光陽, 永瀬丈嗣, 中野貴由
    • Organizer
      軽金属学会70周年中国四国支部記念事業
    • Related Report
      2022 Annual Research Report
  • [Presentation] TiZrHfAlxミディアムエントロピー合金の開発とその生体材料としての可能性2022

    • Author(s)
      高橋凪, 當代光陽, 永瀬丈嗣, 松垣あいら, 中野貴由
    • Organizer
      日本材料科学会四国支部第30回講演大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] (TiZr)x(TaZrMo)2-x高エントロピー合金の等軸デンドライト組織とヤング率2022

    • Author(s)
      當代光陽, 髙橋凪, 川堀龍, 永瀬丈嗣, 中野貴由
    • Organizer
      軽金属学会第143回秋期講演大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 生体用Bcc 型TiNbTaZrMo ハイエントロピー合金における等軸デンドライト組織とヤング率の制御2022

    • Author(s)
      當代光陽, 川堀龍, 高橋凪, 永瀬丈嗣, 松垣あいら, 中野貴由
    • Organizer
      日本金属学会2023年春季講演大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Kinetic Arrest of B2-R and R-B19' Martensitic Transformations in Ti-(50-x)Ni-xFe Shape Memory Alloys2021

    • Author(s)
      ○M. Todai, T. Fukuda, T. Kakeshita
    • Organizer
      16th Inaternational Conference on Martensitic Transformation (ICOMAT2022)
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] hcp型TiZrHfAl系BioMEAの開発2021

    • Author(s)
      ○高橋凪, 田中音色, 當代光陽, 松垣あいら, 永瀬丈嗣, 中野貴由
    • Organizer
      日本金属学会第4回第7分野講演会
    • Related Report
      2021 Research-status Report
  • [Presentation] スタート材として合金粉末を使用しないレーザ積層造形法によるTi-Nb超伝導材料の開発2021

    • Author(s)
      ○高橋直哉, 當代光陽, 永瀬丈嗣, 中野貴由
    • Organizer
      軽金属学会70周年中国四国支部記念事業
    • Related Report
      2021 Research-status Report
  • [Presentation] 合金粉末を使用しないTi-Nb合金のレーザ積層造形2021

    • Author(s)
      ○越智侑七, 加藤梨紗, 當代光陽, 永瀬 丈嗣, 中野 貴由
    • Organizer
      粉体粉末冶金協会2021年度秋季大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 合金粉末を使用しない金属積層造形法(金属3Dプリンタ)技術と金属組織制御2021

    • Author(s)
      ○當代光陽, 永瀬丈嗣, 中野貴由
    • Organizer
      KOSEN EXPO
    • Related Report
      2021 Research-status Report
  • [Presentation] Drowing on micro size marks for digital image correlation methods by femtosecond laser lightgraphic technique2020

    • Author(s)
      R. Ando, M. Todai, J. Narshima, M. Mizoshiri
    • Organizer
      5th STI-Gigaku 2020
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Controlling the Young’s modulus of bio-high entropy alloys with bcc2020

    • Author(s)
      T. Kawabori, M. Todai, T. Nagase, M. Mizoshiri, T. Nakano
    • Organizer
      5th STI-Gigaku 2020
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] bcc型TiNbTaZrMo系ハイエントロピー合金へのB添加の影響2020

    • Author(s)
      川堀龍, 當代光陽, 永瀬 丈嗣, 中野 貴由
    • Organizer
      日本金属学会2021年春季講演大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 合金粉末を必要としないTi-Nb超伝導材料のレーザ積層造形法2020

    • Author(s)
      越智侑七, 加藤梨紗, 當代光陽, 永瀬丈嗣, 中野貴由
    • Organizer
      日本金属学会2021年春季講演大会
    • Related Report
      2020 Research-status Report
  • [Presentation] bcc型TiNbTaZrMo BioHEAの力学特性向上に向けた合金設計2020

    • Author(s)
      當代光陽, 川堀龍, 永瀬丈嗣, 中野貴由
    • Organizer
      日本金属学会2021年春季講演大会
    • Related Report
      2020 Research-status Report
  • [Presentation] Controlling the Young’s modulus in TiNbTaZrMo bio-high entropy alloys2020

    • Author(s)
      T. Kawabori, M. Todai, T. Nagase, T. Nakano
    • Organizer
      30th MRSJ annual meeting
    • Related Report
      2020 Research-status Report
  • [Presentation] Fabrication of the Ti-Nb superconductive materials from mixture powder via SLM2020

    • Author(s)
      Y. Ochi, R. Kato, M. Todai, T. Nagase, T. Nakano
    • Organizer
      30th MRSJ annual meeting
    • Related Report
      2020 Research-status Report
  • [Presentation] レーザ積層造形法によるBioHEAの作製と特異組織形成2020

    • Author(s)
      中野加菜, 小笹良輔, 石本卓也, 松垣あいら, 永瀬丈嗣, 當代光陽, 中野貴由
    • Organizer
      日本金属学会2020年秋季講演大会
    • Related Report
      2020 Research-status Report
  • [Book] デジタル化時代のAdditive Manufacturingの基礎と応用【第2版】2023

    • Author(s)
      中野貴由, 桐原聡秀, 近藤勝義, 西川宏, 田中学
    • Total Pages
      311
    • Publisher
      一般社団法人スマートプロセス学会
    • Related Report
      2022 Annual Research Report
  • [Book] デジタル化時代のAdditive Manufacturingの基礎と応用2022

    • Author(s)
      中野貴由、桐原聡秀、近藤勝義、西川宏、田中学
    • Total Pages
      326
    • Publisher
      リブロ社
    • Related Report
      2021 Research-status Report
  • [Book] 機能性材料科学入門2021

    • Author(s)
      石井 知彦、楠瀬 尚史、鶴町 徳昭、舟橋 正浩、松本 洋明、宮川 勇人
    • Total Pages
      264
    • Publisher
      共立出版
    • ISBN
      9784320071995
    • Related Report
      2021 Research-status Report
  • [Remarks] 新居浜高専當代研究室

    • URL

      https://www.mat.niihama-nct.ac.jp/~todai/

    • Related Report
      2022 Annual Research Report
  • [Remarks] 新居浜工業高等専門学校環境材料工学科

    • URL

      https://www.mat.niihama-nct.ac.jp/

    • Related Report
      2022 Annual Research Report
  • [Remarks] 新居浜工業高等専門学校

    • URL

      https://www.niihama-nct.ac.jp/

    • Related Report
      2022 Annual Research Report
  • [Remarks] 新居浜高専環境材料工学科當代研究室

    • URL

      https://www.mat.niihama-nct.ac.jp/~todai/

    • Related Report
      2021 Research-status Report
  • [Remarks] 新居浜工業高等専門学校HP

    • URL

      https://www.niihama-nct.ac.jp/

    • Related Report
      2020 Research-status Report
  • [Remarks] 新居浜工業高等専門学校環境材料工学科HP

    • URL

      https://www.mat.niihama-nct.ac.jp/

    • Related Report
      2020 Research-status Report

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Published: 2020-04-28   Modified: 2024-01-30  

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