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Prediction system for severity of pneumonitis after radiotherapy for lung cancer and optimization of treatment methods using deep learning

Research Project

Project/Area Number 20K08113
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionKyushu University

Principal Investigator

Shioyama Yoshiyuki  九州大学, 医学研究院, 共同研究員 (10323304)

Co-Investigator(Kenkyū-buntansha) 佐々木 智成  株式会社麻生(株式会社麻生飯塚病院医学研究推進本部), 放射線科, 部長 (10380437)
有村 秀孝  九州大学, 医学研究院, 教授 (20287353)
吉武 忠正  九州大学, 大学病院, 講師 (40452750)
松本 圭司  九州大学, 医学研究院, 助教 (40467907)
白川 友子 (イソヤマ友子)  九州大学, 医学研究院, 共同研究員 (40529830)
浅井 佳央里  九州大学, 大学病院, 助教 (40635471)
廣瀬 貴章  九州大学, 大学病院, 診療放射線技師 (50608982)
Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2023: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2022: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2021: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords肺癌 / 放射線肺臓炎 / 深層学習 / ラディオミクス / 重症度予測 / 再発リスク予測 / 治療法の最適化 / 治療法最適化
Outline of Research at the Start

高精度放射線治療では線量分布が非常に複雑で、既存肺の状態や基礎疾患など患者側因子や併用薬物療法等も影響するため、特的の線量-体積パラメータのみで患者毎のリスクを正確に予測するのは困難である。肺癌放射線治療症例の精密な臨床免疫学的情報、既存肺の画像特徴量(ラディオミクス)および治療情報からなるビッグデータを多層ニューラルネットワークによる機械学習(いわゆる深層学習)の手法を用いて解析し、放射線肺臓炎リスク予測および照射法最適化のシステムを構築する。

Outline of Final Research Achievements

We performed to developed a prediction model of RP using CT imaging features for stereotactic radiotherapy of early-stage lung cancer and showed the usefulness of combining serum KL-6, a marker of interstitial pneumonia, with CT imaging features.
We also showed that CT imaging features can predict the risk of recurrence after stereotactic radiotherapy. Furthermore, we examined whether the combined use of radiomics score and various clinical factors (age, gender, PS, histological type, tumor size, etc.) can predict the risk of local recurrence and distant metastasis more accurately. The results suggest that the risk of recurrence and its pattern (local recurrence, distant metastasis) after stereotactic irradiation of lung cancer can be predicted by using the radiomic score in addition to the histological type and tumor size.

Academic Significance and Societal Importance of the Research Achievements

肺癌放射線治療において最も重要な有害事象の一つと考えられている放射線肺臓炎に関連する臨床因子および線量・体積パラメータ等は報告されているが, 患者毎にそのリスクを正確に予測し治療方法に反映することは困難である. また, 治療後の予後予測因子に関する研究も多く行われているが、再発形式を含めたリスク予測に関する研究は少ない. 治療法の最適化には,安全性と有効性のバランスが重要で, 両者をどちらも予測することが重要である. CT画像特徴量、臨床因子等を組合わせることで, 症例毎に放射線肺臓炎や再発形式を含めたリスク予測が可能となることが示唆され, 本領域の精密医療の進歩に貢献するものと考えられる.

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (48 results)

All 2024 2023 2022 2021 2020

All Journal Article (21 results) (of which Int'l Joint Research: 7 results,  Peer Reviewed: 18 results,  Open Access: 16 results) Presentation (24 results) (of which Int'l Joint Research: 3 results,  Invited: 12 results) Book (3 results)

  • [Journal Article] Five-Year Survival Outcomes After Carbon-Ion Radiotherapy for Operable Stage I NSCLC: A Japanese National Registry Study (J-CROS-LUNG)2024

    • Author(s)
      Kubo Nobuteru、Suefuji Hiroaki、Nakajima Mio、Tokumaru Sunao、Okano Naoko、Yoshida Daisaku、Suzuki Osamu、Ishikawa Hitoshi、Satouchi Miyako、Nakayama Haruhiko、Shimizu Kimihiro、Shioyama Yoshiyuki
    • Journal Title

      Journal of Thoracic Oncology

      Volume: 19 Issue: 3 Pages: 491-499

    • DOI

      10.1016/j.jtho.2023.10.016

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical results of carbon ion radiotherapy for inoperable stage I non-small cell lung cancer: A Japanese national registry study (J-CROS-LUNG)2023

    • Author(s)
      Kubo Nobuteru、Suefuji Hiroaki、Nakajima Mio、Tokumaru Sunao、Okano Naoko、Yoshida Daisaku、Suzuki Osamu、Ishikawa Hitoshi、Satouchi Miyako、Nakayama Haruhiko、Shioyama Yoshiyuki
    • Journal Title

      Radiotherapy and Oncology

      Volume: 183 Pages: 109640-109640

    • DOI

      10.1016/j.radonc.2023.109640

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical results of carbon-ion radiotherapy for stage I non-small cell lung cancer with concomitant interstitial lung disease: a Japanese national registry study (J-CROS-LUNG)2023

    • Author(s)
      Okano Naoko、Suefuji Hiroaki、Nakajima Mio、Tokumaru Sunao、Kubo Nobuteru、Yoshida Daisaku、Suzuki Osamu、Ishikawa Hitoshi、Satouchi Miyako、Nakayama Haruhiko、Shioyama Yoshiyuki
    • Journal Title

      Journal of Radiation Research

      Volume: 64 Issue: Supplement_1 Pages: i2-i7

    • DOI

      10.1093/jrr/rrad008

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Difference in target dose distributions between Acuros XB and collapsed cone convolution/superposition and the impact of the tumor locations in clinical cases of stereotactic ablative body radiotherapy for lung cancer2023

    • Author(s)
      Inoue Keiki、Matsukawa Hideaki、Kasai Yuki、Edamitsu Kana、Matsumoto Kazuki、Suetsugu Yoshiki、Hirose Taka-aki、Fukunaga Jun-ichi、Shioyama Yoshiyuki、Sasaki Tomonari
    • Journal Title

      Journal of Cancer Research and Therapeutics

      Volume: 19 Issue: 5 Pages: 1261-1266

    • DOI

      10.4103/jcrt.jcrt_1740_21

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparative Analysis of Photon Stereotactic Radiotherapy and Carbon-Ion Radiotherapy for Elderly Patients with Stage I Non-Small-Cell Lung Cancer: A Multicenter Retrospective Study2023

    • Author(s)
      Aoki S, Onishi H, Karube M, Yamamoto N, Yamashita H, Shioyama Y, Matsumoto Y, Matsuo Y, Miyakawa A, Matsushita H, Ishikawa H.
    • Journal Title

      Cancers (Basel)

      Volume: 15143633 Issue: 14 Pages: 3633-3633

    • DOI

      10.3390/cancers15143633

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Deep learning model fusion improves lung tumor segmentation accuracy across variable training-to-test dataset ratios2023

    • Author(s)
      Cui Yunhao、Arimura Hidetaka、Yoshitake Tadamasa、Shioyama Yoshiyuki、Yabuuchi Hidetake
    • Journal Title

      Physical and Engineering Sciences in Medicine

      Volume: 46 Issue: 3 Pages: 1271-1285

    • DOI

      10.1007/s13246-023-01295-8

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Real-World Results of Stereotactic Body Radiotherapy for 399 Medically Operable Patients with Stage I Histology-Proven Non-Small Cell Lung Cancer2023

    • Author(s)
      Onishi H, Shioyama Y, Matsumoto Y, Matsuo Y, Miyakawa A, Yamashita H, Matsushita H, Aoki M, Nihei K, Kimura T, Ishiyama H, Murakami N, Nakata K, Takeda A, Uno T, Nomiya T, Taguchi H, Seo Y, Komiyama T, Marino K, Aoki S, Matsuda M, Akita T, Saito M.
    • Journal Title

      Cancers

      Volume: 15 Issue: 17 Pages: 4382-4382

    • DOI

      10.3390/cancers15174382

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The impact of the <scp>COVID</scp>‐19 pandemic on radiotherapy delivery in Japan: An observational study based on the national database2023

    • Author(s)
      Tamari Keisuke、Kishigami Maiko、Nagata Yasushi、Mizowaki Takashi、Kodaira Takeshi、Onishi Hiroshi、Ogawa Kazuhiko、Shioyama Yoshiyuki、Shigematsu Naoyuki、Uno Takashi
    • Journal Title

      Cancer Medicine

      Volume: 12 Issue: 22 Pages: 21032-21040

    • DOI

      10.1002/cam4.6661

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Combination of Clinical Factors and Radiomics Can Predict Local Recurrence and Metastasis After Stereotactic Body Radiotherapy for Non-small Cell Lung Cancer2023

    • Author(s)
      ISOYAMA-SHIRAKAWA YUKO、YOSHITAKE TADAMASA、NINOMIYA KENTA、ASAI KAORI、MATSUMOTO KEIJI、SHIOYAMA YOSHIYUKI、KODAMA TAKUMI、ISHIGAMI KOUSEI、ARIMURA HIDETAKA
    • Journal Title

      Anticancer Research

      Volume: 43 Issue: 11 Pages: 5003-5013

    • DOI

      10.21873/anticanres.16699

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 肺癌治療の新時代ー粒子線治療2023

    • Author(s)
      塩山善之、末藤大明、松延 亮、寺嶋広太郎、戸山真吾、福西かおり、太田稚奈、今福 輝奈, 今福輝
    • Journal Title

      臨床と研究

      Volume: 100 (8) Pages: 973-979

    • Related Report
      2023 Annual Research Report
  • [Journal Article] Establishing quality indicators to comprehensively assess quality assurance and patient safety in radiotherapy and their relationship with an institution's background2023

    • Author(s)
      Mizuno Norifumi、Okamoto Hiroyuki、Minemura Toshiyuki、Kawamura Shinji、Tohyama Naoki、Kurooka Masahiko、Kawamorita Ryu、Nakamura Masaru、Ito Yoshinori、Shioyama Yoshiyuki、Aoyama Hidefumi、Igaki Hiroshi
    • Journal Title

      Radiotherapy and Oncology

      Volume: 179 Pages: 109452-109452

    • DOI

      10.1016/j.radonc.2022.109452

    • Related Report
      2022 Research-status Report
    • Peer Reviewed
  • [Journal Article] Relapse predictability of topological signature on pretreatment planning <scp>CT</scp> images of stage I non‐small cell lung cancer patients before treatment with stereotactic ablative radiotherapy2022

    • Author(s)
      Kodama Takumi、Arimura Hidetaka、Shirakawa Yuko、Ninomiya Kenta、Yoshitake Tadamasa、Shioyama Yoshiyuki
    • Journal Title

      Thoracic Cancer

      Volume: 13 Issue: 15 Pages: 2117-2126

    • DOI

      10.1111/1759-7714.14483

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Synergistic combination of a topologically invariant imaging signature and a biomarker for the accurate prediction of symptomatic radiation pneumonitis before stereotactic ablative radiotherapy for lung cancer: A retrospective analysis2022

    • Author(s)
      K. Ninomiya, H. Arimura, T. Yoshitake, T. Hirose and Y. Shioyama
    • Journal Title

      PLoS One

      Volume: - Issue: 1 Pages: e0263292-e0263292

    • DOI

      10.1371/journal.pone.0263292

    • Related Report
      2022 Research-status Report 2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 放射線治療における深層学習の応用2022

    • Author(s)
      塩山善之,二宮健太, 廣瀬貴章, 兒玉拓巳, 吉武忠正, 有村秀孝
    • Journal Title

      日本臨牀 最新臨床肺癌学 ―診断・治療の最新動向― V. 治療

      Volume: 80 (増刊号8) Pages: 477-483

    • Related Report
      2022 Research-status Report
  • [Journal Article] Automated approach for segmenting gross tumor volumes for lung cancer stereotactic body radiation therapy using CT-based dense V-networks2021

    • Author(s)
      Cui Yunhao、Arimura Hidetaka、Nakano Risa、Yoshitake Tadamasa、Shioyama Yoshiyuki、Yabuuchi Hidetake
    • Journal Title

      Journal of Radiation Research

      Volume: 62 Issue: 2 Pages: 346-355

    • DOI

      10.1093/jrr/rraa132

    • Related Report
      2021 Research-status Report 2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Impact of pre-treatment C-reactive protein level and skeletal muscle mass on outcomes after stereotactic body radiotherapy for T1N0M0 non-small cell lung cancer: a supplementary analysis of the Japan Clinical Oncology Group study JCOG04032021

    • Author(s)
      Matsuo Yukinori、Nagata Yasushi、Wakabayashi Masashi、Ishikura Satoshi、Onishi Hiroshi、Kokubo Masaki、Karasawa Katsuyuki、Shioyama Yoshiyuki、Onimaru Rikiya、Hiraoka Masahiro
    • Journal Title

      Journal of Radiation Research

      Volume: 62 Issue: 5 Pages: 901-909

    • DOI

      10.1093/jrr/rrab065

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 肺癌定位放射線治療における治療計画 CT 画像を用いた レディオミクス解析による放射線肺臓炎予測2021

    • Author(s)
      廣瀬 貴章、有村 秀孝、二宮 健太、吉武 忠正、福永 淳一、塩山 善之
    • Journal Title

      医用画像情報学会雑誌

      Volume: 38 Pages: 41-45

    • NAID

      130008062562

    • Related Report
      2021 Research-status Report
  • [Journal Article] Gefitinib induction followed by chemoradiotherapy in EGFR-mutant, locally advanced non-small-cell lung cancer: LOGIK0902/OLCSG0905 phase II study2021

    • Author(s)
      Hotta K.、Saeki S.、Yamaguchi M.、Harada D.、Bessho A.、Tanaka K.、Inoue K.、Gemba K.、Shiojiri M.、Kato Y.、Ninomiya T.、Kubo T.、Kishimoto J.、Shioyama Y.、Katsui K.、Sasaki J.、Kiura K.、Sugio K.
    • Journal Title

      ESMO Open

      Volume: 6 Issue: 4 Pages: 100191-100191

    • DOI

      10.1016/j.esmoop.2021.100191

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Radiomic prediction of radiation pneumonitis on pretreatment planning computed tomography images prior to lung cancer stereotactic body radiation therapy2020

    • Author(s)
      Hirose Taka-aki、Arimura Hidetaka、Ninomiya Kenta、Yoshitake Tadamasa、Fukunaga Jun-ichi、Shioyama Yoshiyuki
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 20424-20424

    • DOI

      10.1038/s41598-020-77552-7

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Similar-cases-based planning approaches with beam angle optimizations using water equivalent path length for lung stereotactic body radiation therapy2020

    • Author(s)
      Haseai Shu、Arimura Hidetaka、Asai Kaori、Yoshitake Tadamasa、Shioyama Yoshiyuki
    • Journal Title

      Radiological Physics and Technology

      Volume: 13 Issue: 2 Pages: 119-127

    • DOI

      10.1007/s12194-020-00558-3

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Stereotactic body radiotherapy in patients with lung tumors composed of mainly ground-glass opacity2020

    • Author(s)
      Onishi H、Shioyama Y、Matsumoto Y、Shibamoto Y、Miyakawa A、Suzuki G、Nishimura Y、Sasaki R、Miyawaki D、Kuriyama K、Komiyama T、Marino K、Aoki S、Saito R、Araya M、Maehata Y、Nonaka H、Tominaga L、Saito M、Sano N、Yamada S
    • Journal Title

      Journal of Radiation Research

      Volume: 61 Issue: 3 Pages: 426-430

    • DOI

      10.1093/jrr/rraa015

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 肺がん高精度放射線治療の現況と展望 - 骨転移診療も含めて -2024

    • Author(s)
      塩山善之
    • Organizer
      第27回 七隈癌治療フォーラム
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 肺癌に対する高精度放射線治療の現状と展望2023

    • Author(s)
      塩山善之
    • Organizer
      第64回日本肺癌学会学術集会
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 非小細胞肺癌術後の局所再発に対する 重粒子線治療2023

    • Author(s)
      福西かおり、松延 亮、末藤大明 寺嶋広太郎、戸山真吾、太田稚奈、塩山善之
    • Organizer
      第64回日本肺癌学会学術集会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 頭頸部・気管食道領域癌に対する粒子線治療2023

    • Author(s)
      塩山善之
    • Organizer
      第74回日本気管食道科学会総会・学術講演会
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 非小細胞肺癌術後の局所再発に対する 救済重粒子線治療2023

    • Author(s)
      福西かおり、松延 亮、末藤大明 寺嶋広太郎、戸山真吾、太田稚奈、塩山善之
    • Organizer
      日本放射線腫瘍学会第36回高精度放射線外部照射部会学術大会
    • Related Report
      2022 Research-status Report
  • [Presentation] Current Status of Carbon-ion Radiotherapy for Early-stage Lung cancer2022

    • Author(s)
      Yoshiyuki Shioyama
    • Organizer
      第35回日本放射線腫瘍学会学術大会
    • Related Report
      2022 Research-status Report
    • Invited
  • [Presentation] Pretreatment Prediction of Radiation Pneumonitis Based on Radiomics and Deep Learning after Lung Cancer Stereotactic Body Radiation Therapy2022

    • Author(s)
      Taka-aki Hirose, Hidetaka Arimura, Yunhao Cui, Kenta Ninomiya, Tadamasa Yoshitake, Jun-ichi Fukunaga, Yoshiyuki Shioyama
    • Organizer
      The American Association of Physicists in Medicine (AAPM) 64th Annual Meeting
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Combination of clinical factors and radiomics can predict recurrence patterns after stereotactic body radiotherapy for non-small cell lung cancer2022

    • Author(s)
      Yuko Isoyama-Shirakawa, Tadamasa Yoshitake, Kenta Ninomiya, Kaori Asai, Yoshiyuki Shioyama, Kousei Ishigami, Hidetaka Arimura
    • Organizer
      第81回日本医学放射線学会総会
    • Related Report
      2022 Research-status Report
  • [Presentation] 間質性肺炎合併早期肺癌に対する粒子線治療2022

    • Author(s)
      塩山善之、松延 亮、末藤大明、寺嶋広太郎、戸山真吾、福西かおり
    • Organizer
      第63回日本肺癌学会学術集会 ワークショップ:間質性肺炎合併肺癌の急性増悪に挑む
    • Related Report
      2022 Research-status Report
    • Invited
  • [Presentation] 間質性肺炎合併肺癌に対する粒子線治療2022

    • Author(s)
      塩山 善之, 松延 亮, 末藤 大明, 寺嶋 広太郎, 戸山 真吾, 福西 かおり, 太田 稚奈
    • Organizer
      第89回日本呼吸器学会・日本結核 非結核性抗酸菌症学会・ 日本サルコイドーシス/肉芽腫性疾患学会 九州支部秋季学術講演会 シンポジウム:間質性肺炎合併肺癌の治療戦略
    • Related Report
      2022 Research-status Report
    • Invited
  • [Presentation] 肺癌の粒子線治療2022

    • Author(s)
      塩山 善之
    • Organizer
      第62回日本肺癌学会九州支部学術集会/第45回日本呼吸器内視鏡学会九州支部総会
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] 非小細胞肺癌術後の局所再発に対する救済重粒子線治療2022

    • Author(s)
      福西かおり、松延 亮、末藤 大明、寺嶋広太郎、戸山 真吾、塩山 善之
    • Organizer
      第62回日本肺癌学会九州支部学術集会/第45回日本呼吸器内視鏡学会九州支部総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 重粒子線がん治療の現状と展望2021

    • Author(s)
      塩山 善之、末藤 大明、松延 亮、寺嶋 広太郎、戸山 真吾、福西 かおり
    • Organizer
      第1回 日本量子医科学会 学術大会
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] 肺癌に対する最新放射線療法2021

    • Author(s)
      塩山 善之
    • Organizer
      第77回日本放射線技術学会総会学術大会
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] Deep Learning-Based Prediction of Radiation Pneumonitis after Lung Cancer Stereotactic Body Radiation Therapy2021

    • Author(s)
      Taka-aki Hirose, Hidetaka Arimura, Yunhao Cui, Kenta Ninomiya, Tadamasa Yoshitake, Jun-ichi Fukunaga, Yoshiyuki Shioyama
    • Organizer
      第77回日本放射線技術学会総会学術大会
    • Related Report
      2021 Research-status Report
  • [Presentation] Pretreatment Prediction of Radiation Pneumonitis Based on Deep Transfer Learning after Lung Cancer Stereotactic Body Radiation Therapy2021

    • Author(s)
      Taka-aki Hirose, Hidetaka Arimura, Yunhao Cui, Kenta Ninomiya, Tadamasa Yoshitake, Jun-ichi Fukunaga, Yoshiyuki Shioyama
    • Organizer
      The 9th Korea-Japan Joint Meeting on Medical Physics
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] 肺癌に対する放射線療法2021

    • Author(s)
      塩山善之
    • Organizer
      第61回日本肺癌学会九州支部学術集会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 炭素イオン線治療における肺尖部腫瘍への呼吸による線量影響の評価2021

    • Author(s)
      小松和樹, 林 直紀, 岡本 圭, 垣内玄雄, 佐藤弘史, 寺嶋広太郎, 塩山善之
    • Organizer
      日本放射線腫瘍学会第34回高精度放射線外部照射部会学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 大腸癌肺転移に対する体幹部定位放射線治療成績2020

    • Author(s)
      浅井佳央里, 吉武忠正, 松本圭司, 白川友子, 稲盛真人, 中島孝彰, 塩山善之
    • Organizer
      日本放射線腫瘍学会第33回高精度放射線外部照射部会学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] ディープラーニングを用いた骨盤内リンパ節領域の自動抽出システムの構築と検証2020

    • Author(s)
      吉武忠正, 浅井佳央里, 松本圭司, 白川友子, 稲盛真人, 中島孝彰, 長谷川 悠, 佐々木智成, 西江昭宏, 塩山善之
    • Organizer
      日本放射線腫瘍学会第33回高精度放射線外部照射部会学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 肺癌に対する放射線療法における最近の進歩~Recent developments of radiotherapy for lung cancer~2020

    • Author(s)
      塩山善之
    • Organizer
      第79回日本医学放射線学会総会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] CT-Radiomics特徴量を用いた非小細胞肺癌定位照射後の放射線肺臓炎予測2020

    • Author(s)
      廣瀬貴章, 有村秀孝, 二宮健太, 吉武忠正, 福永淳一, 塩山善之
    • Organizer
      日本放射線腫瘍学会第33回学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] Radiomic prediction of radiation pneumonitis on pretreatment planning CT images of lung cancer patients receiving stereotactic body radiation therapy2020

    • Author(s)
      Taka-aki Hirose, Hidetaka Arimura, Kenta Ninomiya, Tadamasa Yoshitake, Jun-ichi Fukunaga, Yoshiyuki Shioyama
    • Organizer
      American Association of Physicists in Medicine (AAPM) Annual Meeting 2020
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Radiomic prediction of radiation pneumonitis in patients receiving stereotactic body radiation therapy for lung cancer2020

    • Author(s)
      Taka-aki Hirose, Hidetaka Arimura, Kenta Ninomiya, Tadamasa Yoshitake, Jun-ichi Fukunaga, Yoshiyuki Shioyama
    • Organizer
      第119回日本医学物理学会学術大会
    • Related Report
      2020 Research-status Report
  • [Book] Stereotactic Body Radiation Therapy; Principles and Practices, Yasushi Nagata Editor2023

    • Author(s)
      Tadamasa Yoshitake, Akira Matsunobu, Yoshiyuki Shioyama
    • Total Pages
      325
    • Publisher
      Springer
    • ISBN
      9789819939787
    • Related Report
      2023 Annual Research Report
  • [Book] がん・放射線療法 改訂第8版 大西 洋、唐澤 久美子、石川 仁、西尾 禎治 編集2023

    • Author(s)
      塩山善之,辻 比呂志
    • Total Pages
      1386
    • Publisher
      Gakken
    • ISBN
      9784055200493
    • Related Report
      2023 Annual Research Report
  • [Book] 放射線治療学 改訂第7版 井上 俊彦、小川 和彦、小泉 雅彦 編集2023

    • Author(s)
      塩山善之
    • Total Pages
      481
    • Publisher
      南山堂
    • ISBN
      9784525270971
    • Related Report
      2023 Annual Research Report

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Published: 2020-04-28   Modified: 2025-01-30  

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