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Clinical Utility of a Behavioral Task to Measure Metacognition in Patients with Traumatic Brain Injury

Research Project

Project/Area Number 20K11178
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59010:Rehabilitation science-related
Research InstitutionHokkaido University

Principal Investigator

Kazuki Yoshida  北海道大学, 保健科学研究院, 講師 (90638280)

Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2022: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2021: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywordsメタ認知 / 外傷性脳損傷 / 自己認識 / 認知機能障害 / MRI / 行動評価 / セルフアウェアネス / 神経心理学的検査
Outline of Research at the Start

脳損傷者はしばしばメタ認知の障害を呈する。メタ認知とは自身を客観的に認知する能力であり、自身の障害や能力に対する認識や行動のモニタリングが含まれる。メタ認知の障害はリハビリテーションの阻害要因であり、患者の転帰に影響することが知られているが、メタ認知を定量的に測定できる行動評価がないのが現状である。本研究の目的は、メタ認知を定量的に測定できる行動評価を作成し、外傷性脳損傷患者を対象に、その臨床的有用性を検討することである。また、自身の障害や能力に対する認識の障害と行動モニタリングとの関連性に関しても検討する。

Outline of Final Research Achievements

This study revealed that (1) patients after traumatic brain injury (TBI) were less metacognitive efficiency than healthy controls, (2) patients after TBI tend to be over confident compared to healthy controls, (3) metacognitive efficiency was related to clinical self-awareness ratings but not to other neuropsychological tests, and (4) lower metacognitive ability was associated with left frontal brain injury. These results contribute to our understanding of the pathology of metacognitive deficits in patients after TBI. Correlations with clinical self-awareness ratings also suggested the clinical utility of behavioral metacognitive measures.

Academic Significance and Societal Importance of the Research Achievements

メタ認知機能の低下は自身の行動や認知の客観的な評価の不正確さにつながり、適応的行動に必要だと考えられている。外傷性脳損傷患者の不適切な行動や認知はメタ認知能力の低下と関連している可能性がある。本研究では外傷性脳損傷患者はメタ認知機能の低下を示すこと、患者の自己評価は自信過剰な方向に偏っていること、メタ認知能力は臨床的な自己認識評価と相関するが神経心理学的検査とは相関しないこと、左前頭部の損傷がメタ認知能力低下と関連しうることなど、病態理解に貢献する複数の知見を得た。これらは患者のより適切な評価やメタ認知を対象とした新たな介入手法の開発につながる可能性がある。

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • Research Products

    (26 results)

All 2023 2022 2021 2020

All Journal Article (11 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 11 results,  Open Access: 10 results) Presentation (15 results) (of which Int'l Joint Research: 6 results)

  • [Journal Article] Prospective and Retrospective Metacognitive Abilities and Their Association with Impaired Self-awareness in Patients with Traumatic Brain Injury2023

    • Author(s)
      Kazuki Yoshida , Daisuka Sawamura, Keita Ogawa, Takuroh Mototani, Katsunori Ikoma, Shinya Sakai
    • Journal Title

      Journal of Cognitive Neuroscience

      Volume: 35 Issue: 12 Pages: 1960-1971

    • DOI

      10.1162/jocn_a_02064

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Detecting inattentiveness caused by mind-wandering during a driving task: A behavioral study2022

    • Author(s)
      Kazuki Yoshida, Daisuke Sawamura, Yu Nakashima, Ryuji Saito, Nao Yamamura, Katsuhiko Ogasawara, Shinya Sakai
    • Journal Title

      Applied Ergonomics

      Volume: 106 Pages: 103892-103892

    • DOI

      10.1016/j.apergo.2022.103892

    • Related Report
      2023 Annual Research Report 2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Explicit and implicit attitudes toward smoking: Dissociation of attitudes and different characteristics for an implicit attitude in smokers and nonsmokers2022

    • Author(s)
      Gao Xinyue、Sawamura Daisuke、Saito Ryuji、Murakami Yui、Yano Rika、Sakuraba Satoshi、Yoshida Susumu、Sakai Shinya、Yoshida Kazuki
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 10 Pages: e0275914-e0275914

    • DOI

      10.1371/journal.pone.0275914

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Role of the Ventromedial Prefrontal Cortex in Preferential Decisions for Own- and Other-Age Faces2022

    • Author(s)
      Ito Ayahito、Yoshida Kazuki、Aoki Ryuta、Fujii Toshikatsu、Kawasaki Iori、Hayashi Akiko、Ueno Aya、Sakai Shinya、Mugikura Shunji、Takahashi Shoki、Mori Etsuro
    • Journal Title

      Frontiers in Psychology

      Volume: 13 Pages: 822234-822234

    • DOI

      10.3389/fpsyg.2022.822234

    • Related Report
      2022 Research-status Report 2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of Audiovisual Cross-Modal Conflict during Working Memory Tasks: A Near-Infrared Spectroscopy Study2022

    • Author(s)
      Cui Jiahong、Sawamura Daisuke、Sakuraba Satoshi、Saito Ryuji、Tanabe Yoshinobu、Miura Hiroshi、Sugi Masaaki、Yoshida Kazuki、Watanabe Akihiro、Tokikuni Yukina、Yoshida Susumu、Sakai Shinya
    • Journal Title

      Brain Sciences

      Volume: 12 Issue: 3 Pages: 349-349

    • DOI

      10.3390/brainsci12030349

    • Related Report
      2022 Research-status Report 2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Differences of expected intervention effects between participant-led and facilitator-led preventive care services in Japan2021

    • Author(s)
      Yun Shan、Takashima Risa、Yoshida Kazuki、Sawamura Daisuke、Inoue Takao、Sakai Shinya
    • Journal Title

      Hong Kong Journal of Occupational Therapy

      Volume: 34 Issue: 2 Pages: 83-93

    • DOI

      10.1177/15691861211022986

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chopstick operation training with the left non-dominant hand2021

    • Author(s)
      Sawamura Daisuke、Sakuraba Satoshi、Yoshida Kazuki、Hasegawa Naoya、Suzuki Yumi、Yoshida Susumu、Honke Toshihiro、Sakai Shinya
    • Journal Title

      Translational Neuroscience

      Volume: 12 Issue: 1 Pages: 385-395

    • DOI

      10.1515/tnsci-2020-0189

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between the proficiency level and anxiety-reducing effect in a one-time heart rate variability biofeedback2021

    • Author(s)
      Saito Ryuji、Sawamura Daisuke、Yoshida Kazuki、Sakai Shinya
    • Journal Title

      Medicine

      Volume: 100 Issue: 45 Pages: e27742-e27742

    • DOI

      10.1097/md.0000000000027742

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Focused attention meditation training modifies neural activity and attention: longitudinal EEG data in non-meditators2020

    • Author(s)
      Yoshida K, Takeda K, Kasai T, Makinae S, Murakami Y, Hasegawa A, Sakai S
    • Journal Title

      Social Cognitive and Affective Neuroscience

      Volume: 15 Issue: 2 Pages: 215-224

    • DOI

      10.1093/scan/nsaa020

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The role of the ventromedial prefrontal cortex in automatic formation of impression and reflected impression2020

    • Author(s)
      Ito A, Yoshida K, Takeda K, Sawamura D, Murakami Y Hasegawa A, Sakai S, Izuma K
    • Journal Title

      Human Brain Mapping

      Volume: - Issue: 11 Pages: 3045-3058

    • DOI

      10.1002/hbm.24996

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Current practices and factors affecting evidence-based occupational therapy practice for patients with dementia in Japan2020

    • Author(s)
      Hasegawa Ai、Takashima Risa、Yoshida Kazuki、Sawamura Daisuke、Murata Waka、Sakai Shinya
    • Journal Title

      Hong Kong Journal of Occupational Therapy

      Volume: 33 Issue: 2 Pages: 73-81

    • DOI

      10.1177/1569186120980281

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Metacognitive Impairment and Its Association with Self-Awareness in Patients with Traumatic Brain Injury2023

    • Author(s)
      K Yoshida, D Sawamura, K Ogawa, T Mototani, K Ikoma, S Sakai
    • Organizer
      7th European Congress of NeuroRehabilitation
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of heart rate variability biofeedback training on anxiety reduction and its brain activity: an EEG study2023

    • Author(s)
      Ryuji Saito, Kazuki Yoshida, Daisuke Sawamura, Akihiro Watanabe, Yukina Tokikuni, Shinya Sakai
    • Organizer
      7th European Congress of NeuroRehabilitation
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural predictors of the person impression2023

    • Author(s)
      Ayahito Ito, Ryuta Aoki, Akihiro Watanabe, Yukina Tokikuni, Kazuki Yoshida, Yui Murakami, Shunichi Ogawa, Daisuke Sawamura, Hiroyoshi Ogishima, Ryuichi Tamai, Shogo Kajimura, Mie Kito, Masanori Yamanaka, Keise Izuma
    • Organizer
      第46回日本神経科学大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 喫煙に対する明示的、暗黙的態度 -喫煙者、非喫煙者における態度の乖離と暗黙的態度の異なる特徴2022

    • Author(s)
      吉田一生, 高欣悦, 澤村大輔, 齋藤隆司, 村上優衣, 矢野里香, 桜庭聡, 吉田晋, 境信哉
    • Organizer
      第46回日本高次脳機能障害学会
    • Related Report
      2022 Research-status Report
  • [Presentation] 運転課題中のマインドワンダリングによる不注意状態の検出2022

    • Author(s)
      吉田一生, 澤村大輔, 八木幹雄, 中嶋悠, 齊藤隆司, 山村奈央, 小笠原克彦, 境信哉
    • Organizer
      第46回日本高次脳機能障害学会
    • Related Report
      2022 Research-status Report
  • [Presentation] スクロールする日本語黙読時における視線移動の特徴2022

    • Author(s)
      前山昂弥, 澤村大輔, 吉田一生, 鈴木哲平, 小笠原克彦, 境信哉
    • Organizer
      第46回日本高次脳機能障害学会
    • Related Report
      2022 Research-status Report
  • [Presentation] 心拍変動バイオフィードバック訓練による不安低減効果とその脳活動2022

    • Author(s)
      齋藤隆司, 吉田一生, 澤村大輔, 時國幸奈, 渡邉陽裕, 段ビョウ文, 境信哉
    • Organizer
      第46回日本高次脳機能障害学会
    • Related Report
      2022 Research-status Report
  • [Presentation] 外傷性脳損傷患者のメタ認知能力低下の特徴とself-awarenessとの関連2022

    • Author(s)
      吉田一生, 澤村大輔, 小川圭太, 本谷卓郎, 生駒一憲, 境信哉
    • Organizer
      第46回日本神経心理学会
    • Related Report
      2022 Research-status Report
  • [Presentation] Young-age bias in valuation of faces2021

    • Author(s)
      Ayahito Ito, Kazuki Yoshida, Ryuta Aoki, Toshikatsu Fujii, Iori Kawasaki, Akiko Hayashi, Aya Ueno, Etsuro Mori, Shinya Sakai, Shunji Mugikura, Shoki Takahashi, Nobuhito Abe
    • Organizer
      European Society for Cognitive and Affective Neuroscience
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] The role of the ventromedial prefrontal cortex in automatic formation of impression and reflected impression2021

    • Author(s)
      Ayahito Ito, Kazuki Yoshida, Kenta Takeda, Daisuke Sawamura, Yui Murakami, Ai Hasegawa, Shinya Sakai, Keise Izuma
    • Organizer
      32nd International Congress of Psychology
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Comparison of effectiveness between participant-led and facilitator-led preventive care programs in Japan2021

    • Author(s)
      Shan Yun, Risa Takashima, Kazuki Yoshida, Daisuke Sawamura, Shinya Sakai
    • Organizer
      Global Healthcare
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] 顔の印象判断における若年者バイアス ―fMRIとdrift-diffusion modelによる検討―2021

    • Author(s)
      伊藤文人, 吉田一生, 川崎伊織, 境信哉
    • Organizer
      第55回日本作業療法学会
    • Related Report
      2021 Research-status Report
  • [Presentation] Interfering Effect of Cross-modal Conflict During Working Memory Task: A Near-infrared Spectroscopy Study2021

    • Author(s)
      Cui J, Sawamura D, Tanabe Y, MiuraH, Sugi M, Yoshida K, SaitoR, Watanabe A, Tokikuni Y, Sakai S
    • Organizer
      fNIRS 2021 Virtual Meeting
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] 顔の選好判断におけるown-age biasの神経基盤 -機能的MRIとdrift-diffusion modelによる検討-2021

    • Author(s)
      吉田一生、伊藤文人
    • Organizer
      第23回日本ヒト脳機能マッピング学会
    • Related Report
      2020 Research-status Report
  • [Presentation] 腹内側前頭前野における「他者からどう思われそうか」の表象過程2020

    • Author(s)
      伊藤文人, 吉田一生, 武田賢太, 澤村大輔, 村上優衣, 長谷川愛, 境信哉, 出馬圭世
    • Organizer
      第22回日本ヒト脳機能マッピング学会
    • Related Report
      2020 Research-status Report

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Published: 2020-04-28   Modified: 2025-01-30  

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