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Optimal timing and amount of exercise after anterior cruciate ligament reconstruction: focus on joint contracture and muscle atrophy.

Research Project

Project/Area Number 20K19400
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 59010:Rehabilitation science-related
Research InstitutionHiroshima International University

Principal Investigator

Kaneguchi Akinori  広島国際大学, 総合リハビリテーション学部, 助教 (10826704)

Project Period (FY) 2020-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2020: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords膝前十字靭帯損傷 / 膝前十字靭帯再建 / リハビリテーション / 運動 / 関節固定 / 前十字靭帯損傷 / 前十字靭帯再建 / 関節拘縮 / 筋萎縮
Outline of Research at the Start

膝の前十字靭帯(ACL)損傷は、代表的なスポーツ外傷の一つである。スポーツ復帰レベルの回復には再建術が必須となるが、合併症として多くの患者で関節拘縮や筋萎縮に伴う筋力低下が生じ、スポーツ復帰を妨げる。そのため、ACL再建後のリハビリテーションでは、関節拘縮や筋萎縮を予防・改善することが重要となる。しかし、そのために術後どの時期からどの程度運動を行えば良いか、一致した見解は得られていない。
本研究では、ACL再建後の関節固定や運動の影響を調べることにより、どの時期からどの程度運動を行えば良いかを明らかにする。

Outline of Final Research Achievements

The purpose of this study was to determine the effects of joint immobilization and treadmill exercise on joint contracture and muscle atrophy after anterior cruciate ligament reconstruction.
Rats received unilateral knee anterior cruciate ligament reconstruction surgery and were reared without intervention, with joint immobilization, or with daily treadmill exercise (60 minutes/day).
Joint immobilization worsened joint contracture within two weeks. It also adversely affected atrophy of the rectus femoris muscle when performed for four weeks. Treadmill exercise during first two weeks post-surgery worsened joint contracture, while it improved joint contracture when started at two weeks post-surgery. Treadmill exercise could not improve muscle atrophy.

Academic Significance and Societal Importance of the Research Achievements

膝前十字靭帯再建後のリハビリテーションでは、関節拘縮や筋萎縮を予防・改善することが重要となる。しかし、そのために術後どの時期からどの程度運動を行えば良いか、一致した見解は得られていない。
本研究では、前十字靭帯再建後の関節固定とトレッドミル運動が関節拘縮や筋萎縮に及ぼす影響を明らかにした。本研究の結果は、前十字靭帯再建後の効果的なリハビリテーションプログラムの確立につながる重要な基礎データとなると考える。

Report

(3 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • Research Products

    (7 results)

All 2022 2021 2020

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 1 results) Presentation (1 results)

  • [Journal Article] Marrow adipose tissue accumulation and dysgenesis of the trabecular bone after anterior cruciate ligament transection and reconstruction in the rat proximal tibial epiphysis2022

    • Author(s)
      Kaneguchi Akinori、Ozawa Junya、Umehara Takuya、Yamaoka Kaoru
    • Journal Title

      Acta Histochemica

      Volume: 124 Issue: 4 Pages: 151891-151891

    • DOI

      10.1016/j.acthis.2022.151891

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bilateral muscle atrophy after anterior cruciate ligament reconstruction in rats: Protective effects of anti-inflammatory drug celecoxib2022

    • Author(s)
      Kaneguchi Akinori、Umehara Takuya、Yamaoka Kaoru、Ozawa Junya
    • Journal Title

      The Knee

      Volume: 35 Pages: 201-212

    • DOI

      10.1016/j.knee.2022.03.011

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Natural History of Medial Meniscal Tears in the ACL Deficient and ACL Reconstructed Rat Knee2021

    • Author(s)
      Kaneguchi Akinori、Ozawa Junya、Minamimoto Kengo、Yamaoka Kaoru
    • Journal Title

      CARTILAGE

      Volume: 13 Issue: 2_suppl Pages: 1570S-1582S

    • DOI

      10.1177/19476035211014588

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Each Phase of Anterior Cruciate Ligament Reconstruction Surgery on Joint Contracture in Rats2021

    • Author(s)
      Kaneguchi Akinori、Ozawa Junya、Minamimoto Kengo、Yamaoka Kaoru
    • Journal Title

      Journal of Investigative Surgery

      Volume: - Issue: 5 Pages: 984-995

    • DOI

      10.1080/08941939.2021.1985193

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Formation process of joint contracture after anterior cruciate ligament reconstruction in rats2020

    • Author(s)
      Kaneguchi Akinori、Ozawa Junya、Minamimoto Kengo、Yamaoka Kaoru
    • Journal Title

      Journal of Orthopaedic Research

      Volume: - Issue: 5 Pages: 1082-1092

    • DOI

      10.1002/jor.24800

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] ラット膝前十字靭帯再建後の関節腫脹および関節可動域低下に対する低反応レベルレーザー治療の効果2020

    • Author(s)
      金口瑛典、小澤淳也、南本健吾
    • Journal Title

      物理療法科学

      Volume: 27 Pages: 73-77

    • NAID

      40022368196

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Presentation] ラット膝前十字靭帯再建後の荷重量の違いが後肢筋の萎縮に及ぼす影響2021

    • Author(s)
      金口 瑛典、小澤 淳也、下江 淳寛、髙橋 明良、早川 桃伽
    • Organizer
      第26回日本基礎理学療法学会学術大会
    • Related Report
      2021 Annual Research Report

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Published: 2020-04-28   Modified: 2023-01-30  

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