| Budget Amount *help |
¥43,940,000 (Direct Cost: ¥33,800,000、Indirect Cost: ¥10,140,000)
Fiscal Year 2011: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
Fiscal Year 2010: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
Fiscal Year 2009: ¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
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| Research Abstract |
We developed high-sensitivity bio-sensor based on photonic crystal nanolasers with a nano-slot structure. In a test experiment against BSA protein with a low attachment force, a very low detection limit of 255 fM was achieved, suggesting an excellent sensitivity. In a more practical experiment against SA protein, an ultralow concentration of 60 zM was detected without contaminants and<1 aM even with 1 trillion higher concentration BSA as contaminants. These results satisfy the requirements from medical diagnoses for detecting low-concentration bio-markers in human blood.
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