Super-resolution sensing using nanolasers
Project/Area Number |
21246014
|
Research Category |
Grant-in-Aid for Scientific Research (A)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Applied optics/Quantum optical engineering
|
Research Institution | Yokohama National University |
Principal Investigator |
BABA Toshihiko 横浜国立大学, 工学研究院, 教授 (50202271)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥43,940,000 (Direct Cost: ¥33,800,000、Indirect Cost: ¥10,140,000)
Fiscal Year 2011: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
Fiscal Year 2010: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
Fiscal Year 2009: ¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
|
Keywords | ナノレーザ / フォトニック結晶 / バイオフォトニクス / バイオセンシング / ラボオンチップ / GaInAsP / センシング / バイオ |
Research Abstract |
We developed high-sensitivity bio-sensor based on photonic crystal nanolasers with a nano-slot structure. In a test experiment against BSA protein with a low attachment force, a very low detection limit of 255 fM was achieved, suggesting an excellent sensitivity. In a more practical experiment against SA protein, an ultralow concentration of 60 zM was detected without contaminants and<1 aM even with 1 trillion higher concentration BSA as contaminants. These results satisfy the requirements from medical diagnoses for detecting low-concentration bio-markers in human blood.
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Report
(4 results)
Research Products
(60 results)