Synthesis of Biomolecule-Responsive Gels and Construction of Intelligent Biomedical Systems
| Project/Area Number |
21300182
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Kansai University |
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Principal Investigator |
MIYATA Takashi 関西大学, 化学生命工学部, 教授 (50239414)
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| Co-Investigator(Renkei-kenkyūsha) |
IWASAKI Yasuhiko 関西大学, 化学生命工学部, 教授 (90280990)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2009: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
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| Keywords | インテリジェント材料 / 高分子ゲル / 刺激応答性ゲル / バイオコンジュゲーション / ヒドロゲル / 生体分子 / 刺激応答性 / 抗原抗体複合体 / 分子認識 / DDS / 架橋構造 |
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| Research Abstract |
In this study, biomolecule-responsive gels that underwent changes in the volume in response to a signal biomolecule were prepared as smart biomaterials for constructing novel bio-systems. Furthermore, self-regulated drug delivery systems(DDS), diagnostic sensors and so on were developed using biomolecule-responsive gels. We synthesized biomolecule-crosslinked gels and biomolecule-imprinted gels that swell and shrink in response to a signal biomolecule such as an antigen and a saccharide, and tried to apply their gels to DDS and diagnostic sensors.
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Report
(4 results)
Research Products
(70 results)
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[Journal Article]2010
Author(s)
宮田隆志
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Journal Title
CSJカレントレビュー01 驚異のソフトマテリアル-最新の機能性ゲル研究(日本化学会編)(化学同人)
Pages: 97-103
Related Report
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[Journal Article]2009
Author(s)
宮田隆志
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Journal Title
ますます重要になる細胞周辺環境(細胞ニッチ)の最新科学技術(メディカルドゥ)
Pages: 139-145
Related Report
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[Journal Article]2009
Author(s)
宮田隆志
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Journal Title
超分子サイエンス&テクノロジー-基礎からイノベーションまで-(エヌ・ティー・エス出版)
Pages: 454-463
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