Analysis of usefulness of the susceptible mouse strain in higher functional toxicity evaluation of environmental chemicals
Project/Area Number |
21390198
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Hygiene
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Research Institution | National Institute for Environmental Studies |
Principal Investigator |
FUJIMAKI Hidekazu 独立行政法人国立環境研究所, 環境リスク研究センター, 主席研究員 (00124355)
|
Co-Investigator(Kenkyū-buntansha) |
TIN-TIN Win-shwe 独立行政法人国立環境研究所, 環境健康研究センター, 研究員 (00391128)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2011: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2009: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
|
Keywords | 産業衛生 / 環境化学物質 / 脳・神経 / 免疫 / 乳仔期 / 感受性 / 炎症反応 |
Research Abstract |
Using the animal model developed by exposure research of volatile organic compounds, the effects of different chemical on inflammatory response in higher functions were investigated and compared to toluene for verification the usefulness of elucidation of hypersensitivity and searching new biomarkers. It was the same as that of the result of toluene exposure, diazinon exposure during neonatal period affects the nervous and immune functions in later life. Furthermore, the present study showed a new finding indicating that a different pattern of higher functions was found in neonatal diazinon exposure.
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Report
(4 results)
Research Products
(35 results)
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[Presentation] 健康影響と感受性2009
Author(s)
藤巻秀和
Organizer
第50回大気環境学会年会
Place of Presentation
慶応義塾大学日吉キャンパス協生館
Year and Date
2009-09-16
Related Report
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